PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23275304-0	2013	Inhibition of muscle fibrosis and improvement of muscle histopathology in dysferlin knock-out mice treated with halofuginone.	halofuginone	112-124	dysferlin	Mus musculus	74-83	
29771357-0	2018	A promotive effect for halofuginone on membrane repair and synaptotagmin-7 levels in muscle cells of dysferlin-null mice.	halofuginone	23-35	dysferlin	Mus musculus	101-110	
29771357-3	2018	A hypo-osmotic shock assay on myotubes derived from wild-type (Wt) and dysferlin-null (dysf-/-) mice revealed that pre-treatment with halofuginone reduces the percentage of membrane-ruptured myotubes only in dysf-/- myotubes.	halofuginone	134-146	dysferlin	Mus musculus	71-80	
29771357-3	2018	A hypo-osmotic shock assay on myotubes derived from wild-type (Wt) and dysferlin-null (dysf-/-) mice revealed that pre-treatment with halofuginone reduces the percentage of membrane-ruptured myotubes only in dysf-/- myotubes.	halofuginone	134-146	dysferlin	Mus musculus	71-75	
29771357-3	2018	A hypo-osmotic shock assay on myotubes derived from wild-type (Wt) and dysferlin-null (dysf-/-) mice revealed that pre-treatment with halofuginone reduces the percentage of membrane-ruptured myotubes only in dysf-/- myotubes.	halofuginone	134-146	dysferlin	Mus musculus	87-91	
29771357-4	2018	In laser-induced injury of isolated myofibers, halofuginone decreased the amount of FM1-43 at the injury site of dysf-/- myofibers while having no effect on Wt myofibers.	halofuginone	47-59	dysferlin	Mus musculus	113-117	
29771357-5	2018	These results implicate halofuginone in ameliorating muscle-cell membrane integrity in dysf-/- mice.	halofuginone	24-36	dysferlin	Mus musculus	87-91	
29771357-6	2018	Halofuginone increased lysosome scattering across the cytosol of dysf-/- primary myoblasts, in a protein kinase/extracellular signal-regulated protein kinase and phosphoinositide 3 kinase/Akt-dependent manner, in agreement with an elevation in lysosomal exocytotic activity in these cells.	halofuginone	0-12	dysferlin	Mus musculus	65-69	
29771357-8	2018	While halofuginone did not affect patch-repair-complex key proteins, it further enhanced Syt-7 levels and its spread across the cytosol in dysf-/- myofibers and muscle tissue, and increased its co-localization with lysosomes.	halofuginone	6-18	dysferlin	Mus musculus	139-143	
32451154-0	2020	Early pathological signs in young dysf-/- mice are improved by halofuginone.	halofuginone	63-75	dysferlin	Mus musculus	34-38	
23275304-2	2013	We evaluated halofuginone efficacy in improving muscle histopathology in mice with deleted dysf transmembrane domain.	halofuginone	13-25	dysferlin	Mus musculus	91-95	
23275304-3	2013	Quadriceps sublumbar and longissimus muscles of 9-month-old dysf-/- mice treated with halofuginone for 4 months exhibited a reduction in centrally-nucleated myofibers, inflammatory infiltrates and collagen content.	halofuginone	86-98	dysferlin	Mus musculus	60-64