PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14732719-4	2004	In the current study, a small molecular weight molecule, halofuginone (100 nm), is demonstrated by reporter assays to inhibit the TGF-beta signaling pathway, by Northern blotting to elevate inhibitory Smad7 expression within 15 min, and by Western blotting to inhibit formation of phospho-Smad2 and phospho-Smad3 and to decrease cytosolic and membrane TGF-beta type II receptor (TbetaRII).	halofuginone	57-69	transforming growth factor, beta receptor II	Mus musculus	352-377	
14732719-4	2004	In the current study, a small molecular weight molecule, halofuginone (100 nm), is demonstrated by reporter assays to inhibit the TGF-beta signaling pathway, by Northern blotting to elevate inhibitory Smad7 expression within 15 min, and by Western blotting to inhibit formation of phospho-Smad2 and phospho-Smad3 and to decrease cytosolic and membrane TGF-beta type II receptor (TbetaRII).	halofuginone	57-69	transforming growth factor, beta receptor II	Mus musculus	379-387	
14732719-5	2004	Attenuation of TbetaRII levels was noted as early as 1 h and down-regulation persisted for 24 h. Halofuginone blocked TGF-beta-induced delocalization of tight junction ZO-1, a marker of epidermal mesenchymal transition, in NMuMg mammary epithelial cells and suggest halofuginone may have in vivo anti-fibrogenesis characteristics.	halofuginone	97-109	transforming growth factor, beta receptor II	Mus musculus	15-23	
14732719-5	2004	Attenuation of TbetaRII levels was noted as early as 1 h and down-regulation persisted for 24 h. Halofuginone blocked TGF-beta-induced delocalization of tight junction ZO-1, a marker of epidermal mesenchymal transition, in NMuMg mammary epithelial cells and suggest halofuginone may have in vivo anti-fibrogenesis characteristics.	halofuginone	266-278	transforming growth factor, beta receptor II	Mus musculus	15-23	
29156807-5	2017	Halofuginone increased inhibitory Smad7-mRNA and reduced TGF-beta-receptor II protein.	halofuginone	0-12	transforming growth factor, beta receptor II	Mus musculus	57-77