PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20944000-3 2010 For Th17 cells, IDO-mediated tryptophan deprivation and small molecule halofuginone-induced amino acid starvation response were shown to activate general control nonrepressed 2 (GCN2) kinase that directly or indirectly inhibits Th17 cell differentiation. halofuginone 71-83 eukaryotic translation initiation factor 2 alpha kinase 4 Mus musculus 146-176 20944000-3 2010 For Th17 cells, IDO-mediated tryptophan deprivation and small molecule halofuginone-induced amino acid starvation response were shown to activate general control nonrepressed 2 (GCN2) kinase that directly or indirectly inhibits Th17 cell differentiation. halofuginone 71-83 eukaryotic translation initiation factor 2 alpha kinase 4 Mus musculus 178-182 34954499-4 2022 Activation of GCN2 by halofuginone treatment or leucine deprivation decreased NRF2 expression in hepatocytes by increasing GSK-3beta activity. halofuginone 22-34 eukaryotic translation initiation factor 2 alpha kinase 4 Mus musculus 14-18