PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26470720-8	2016	Halofuginone reduced collagen X (Col X), matrix metalloproteinase-13 and A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS 5) and increased lubricin, collagen II and aggrecan.	halofuginone	0-12	matrix metallopeptidase 13	Rattus norvegicus	41-68	
16489207-6	2006	HAL (200 nm) up-regulated matrix metalloproteinase (MMP)-3 and MMP-13 expression between 10- and 50-fold, resulting in a 2- to 3-fold increase of interstitial collagenase activity.	halofuginone	0-3	matrix metallopeptidase 13	Rattus norvegicus	63-69	
16489207-8	2006	p38 mitogen-activated protein kinase (p38 MAPK) and nuclear factor kappaB(NFkappaB) pathways were activated by HAL, and specific inhibitors of p38 MAPK and NFkappaB dose dependently inhibited MMP-13 induction.	halofuginone	111-114	matrix metallopeptidase 13	Rattus norvegicus	192-198