PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31470141-0 2019 Reversine inhibits MMP-3, IL-6 and IL-8 expression through suppression of ROS and JNK/AP-1 activation in interleukin-1beta-stimulated human gingival fibroblasts. 2-(4-morpholinoanilino)-6-cyclohexylaminopurine 0-9 mitogen-activated protein kinase 8 Homo sapiens 82-85 30087398-0 2018 Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1. 2-(4-morpholinoanilino)-6-cyclohexylaminopurine 0-9 mitogen-activated protein kinase 8 Homo sapiens 63-67 30087398-5 2018 A coupled kinase assay with bio-informatics approach identified the c-Jun N-terminal kinase (JNK) cascade as the main pathway inhibited by Reversine. 2-(4-morpholinoanilino)-6-cyclohexylaminopurine 139-148 mitogen-activated protein kinase 8 Homo sapiens 68-91 30087398-5 2018 A coupled kinase assay with bio-informatics approach identified the c-Jun N-terminal kinase (JNK) cascade as the main pathway inhibited by Reversine. 2-(4-morpholinoanilino)-6-cyclohexylaminopurine 139-148 mitogen-activated protein kinase 8 Homo sapiens 93-96 30087398-8 2018 These results highlight the impact of individual JNK isoforms in cancer cell metastasis and propose Reversine as a novel anti-cancer molecule for treatment of colon cancer patients. 2-(4-morpholinoanilino)-6-cyclohexylaminopurine 100-109 mitogen-activated protein kinase 8 Homo sapiens 49-52