PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28468305-0 2017 Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes. magnolin 83-91 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 95-110 21294626-3 2011 In this study, we characterized the human liver cytochrome P450 (CYP) enzymes responsible for the biotransformation of three major metabolites--M1, M2, and M4--of magnolin. magnolin 163-171 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 48-63 21294626-3 2011 In this study, we characterized the human liver cytochrome P450 (CYP) enzymes responsible for the biotransformation of three major metabolites--M1, M2, and M4--of magnolin. magnolin 163-171 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 65-68 21294626-4 2011 CYP2C8, CYP2C9, CYP2C19, and CYP3A4 were identified as the major enzymes responsible for the formation of the two O-desmethyl magnolins (M1 and M2), on the basis of a combination of correlation analysis and experiments, including immunoinhibition of magnolin in human liver microsomes and metabolism of magnolin by human cDNA-expressed CYP enzymes. magnolin 126-134 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-3 21294626-4 2011 CYP2C8, CYP2C9, CYP2C19, and CYP3A4 were identified as the major enzymes responsible for the formation of the two O-desmethyl magnolins (M1 and M2), on the basis of a combination of correlation analysis and experiments, including immunoinhibition of magnolin in human liver microsomes and metabolism of magnolin by human cDNA-expressed CYP enzymes. magnolin 250-258 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-3