PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20376628-13	2010	CONCLUSION: The results suggest that the CYP2C19 genotype contrary to MDR1 and IL-1B genotypes may have an impact on the efficacy of H. pylori eradication in peptic ulcer patients treated with pantoprazole in Polish Caucasian peptic ulcer patients administered pantoprazole, amoxicillin, and metronidazole.	Pantoprazole	193-205	ATP binding cassette subfamily B member 1	Homo sapiens	70-74	
22396185-0	2012	Reversal effects of pantoprazole on multidrug resistance in human gastric adenocarcinoma cells by down-regulating the V-ATPases/mTOR/HIF-1alpha/P-gp and MRP1 signaling pathway in vitro and in vivo.	Pantoprazole	20-32	ATP binding cassette subfamily B member 1	Homo sapiens	144-148	
19139163-2	2009	Previous in vivo studies of the pharmacokinetics of the lipophilic camptothecin (CPT) analog gimatecan suggested that the ATP-binding cassette (ABC) B1 (P-glycoprotein) and/or ABCG2 (breast cancer resistance protein) inhibitors elacridar and pantoprazole could inhibit transporters other than ABCB1 and ABCG2.	Pantoprazole	242-254	ATP binding cassette subfamily B member 1	Homo sapiens	122-151	
29075060-0	2017	Pantoprazole Induces Apoptosis of Leukemic Cells by Inhibiting Expression of P-Glycoprotein/Multidrug Resistance-Associated Protein-1 Through PI3K/AKT/mTOR Signaling.	Pantoprazole	0-12	ATP binding cassette subfamily B member 1	Homo sapiens	77-91	
18089724-7	2007	In Transwell experiments, gimatecan was transported by Bcrp1 and transport was inhibited by the BCRP/P-glycoprotein inhibitors elacridar and pantoprazole.	Pantoprazole	141-153	ATP binding cassette subfamily B member 1	Homo sapiens	101-115	
19139163-6	2009	It is interesting to note that transport of 17beta-estradiol 17beta-d-glucuronide (control), gimatecan, and BNP1350 by OATP1B1 could be completely inhibited by the classic ABCB1 and/or ABCG2 inhibitors elacridar, valspodar, pantoprazole, and, to a lesser extent, zosuquidar and verapamil.	Pantoprazole	224-236	ATP binding cassette subfamily B member 1	Homo sapiens	172-177	
29075060-6	2017	RT-PCR and Western blot analysis indicated that pantoprazole pretreatment inhibited the mRNA and protein expression of p-PI3K, p-Akt, p-mTOR, P-gp and MRP1 in K562/A02 and K562/ADM cells in a dose-dependent manner (p < 0.05).	Pantoprazole	48-60	ATP binding cassette subfamily B member 1	Homo sapiens	142-146	
29075060-7	2017	Pantoprazole arrested cell cycle and induced apoptosis of multidrug resistant leukemic cells by inhibiting the expression of P-gp and MRP1 through PI3K/Akt/mTOR signaling pathway.	Pantoprazole	0-12	ATP binding cassette subfamily B member 1	Homo sapiens	125-129	
27611887-0	2017	Effects of Genetic Polymorphisms of Cytochrome P450 Enzymes and MDR1 Transporter on Pantoprazole Metabolism and Helicobacter pylori Eradication.	Pantoprazole	84-96	ATP binding cassette subfamily B member 1	Homo sapiens	64-68	
27611887-2	2017	Pantoprazole is a substrate for multi-drug resistance protein 1 (MDR1).	Pantoprazole	0-12	ATP binding cassette subfamily B member 1	Homo sapiens	65-69	
27611887-3	2017	Single nucleotide polymorphisms (SNPs) in CYP2C19, CYP3A4 and MDR1 affect enzyme activity or gene expression of proteins and may alter plasma pantoprazole concentrations and treatment success in PUD.	Pantoprazole	142-154	ATP binding cassette subfamily B member 1	Homo sapiens	62-66	
27611887-4	2017	In this study, we aimed to investigate the association between genetic polymorphisms in CYP2C19, CYP3A4 and MDR1 and pharmacokinetics of pantoprazole and therapeutic outcome in patients with either Helicobacter pylori-associated [H.P.	Pantoprazole	137-149	ATP binding cassette subfamily B member 1	Homo sapiens	108-112