PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11139446-2	2000	We have studied in cultured human mesangial cells (CHMC) several effects of 9-cis retinoic acid (9-cRA), an activator of both retinoic acid receptors (RARs) and retinoid X receptors (RXRs).	Alitretinoin	76-95	myotubularin related protein 11	Homo sapiens	99-102	
30108774-6	2017	In contrast the biologically-distinct isomer, 9-cis-retinoic acid (; 9CRA), showed significantly less conformational flexibility in the RAR binding pockets.	Alitretinoin	46-65	myotubularin related protein 11	Homo sapiens	70-73	
22906418-2	2013	This revealed STMN4 and ROBO2 to be consistently up-regulated in differentiated neuroblastoma cells induced by chromosome 1 transfer, MYCN knockdown, and 9-cis retinoic acid (9cRA).	Alitretinoin	154-173	myotubularin related protein 11	Homo sapiens	176-179	
15276068-1	2004	9-cis Retinoic acid (9-CRA) is a lipophilic molecule that binds to the retinoid X receptor (RXR).	Alitretinoin	0-19	myotubularin related protein 11	Homo sapiens	23-26	
11590323-2	2001	We have shown previously that the naturally occurring retinoids all-trans-retinoic acid (ATRA) and 9-cisretinoic acid (9cRA) induce growth inhibition followed by apoptosis in pancreatic adenocarcinoma cells in vitro.	Alitretinoin	99-117	myotubularin related protein 11	Homo sapiens	120-123	
10882139-2	2000	We report the crystal structures of the PPARgamma and RXRalpha LBDs complexed to the RXR ligand 9-cis-retinoic acid (9cRA), the PPARgamma agonist rosiglitazone or GI262570, and coactivator peptides.	Alitretinoin	96-115	myotubularin related protein 11	Homo sapiens	118-121	
10858438-2	2000	In cultured macrophages, ABC1 mRNA was induced in an additive fashion by 22(R)-hydroxycholesterol and 9-cis-retinoic acid (9CRA), suggesting induction by nuclear hormone receptors of the liver X receptor (LXR) and retinoid X receptor (RXR) family.	Alitretinoin	102-121	myotubularin related protein 11	Homo sapiens	124-127	
9806904-12	1998	Under the same reaction conditions, GSTP1-1 was much less effective in catalysing the steric conversion of 9-cis-retinoic acid to t-RA, indicating that the enzyme was stereospecific for the conversion of 13-cRA to t-RA.	Alitretinoin	107-126	myotubularin related protein 11	Homo sapiens	207-210	
10367173-2	1999	PURPOSE: 9-cis retinoic acid (ALRT 1057; 9cRA) is a promising new retinoid that binds to all known retinoic acid receptors (RAR and RXR), potentially providing it with a broader spectrum of biologic activity than either 13-cis retinoic acid or all-trans retinoic acid.	Alitretinoin	9-28	myotubularin related protein 11	Homo sapiens	42-45	
7744246-1	1995	We have identified a new retinoid response pathway through which 9-cis retinoic acid (9cRA) activates transcription in the presence of LXR alpha, a member of the nuclear receptor superfamily.	Alitretinoin	65-84	myotubularin related protein 11	Homo sapiens	87-90	
9791009-5	1998	All-trans (ATRA) and 9-cis retinoic acid (9cRA) reduce c-erbB-1 protein to 50-100%, c-erbB-2 to 20-30%, and c-erbB-3 to 10-50% of control, depending on the concentration, respectively, without influencing the tyrosine phosphorylation status.	Alitretinoin	21-40	myotubularin related protein 11	Homo sapiens	43-46	
8620004-2	1996	RXR, which is activated by 9-cis-retinoic acid (9cRA), can modulate several signaling pathways by virtue of its ability to form heterodimers with other members of the receptor family, as, for example, the retinoic acid receptor (RAR).	Alitretinoin	27-46	myotubularin related protein 11	Homo sapiens	49-52	
9823949-1	1998	The vitamin D analogue KH1060 and the retinoids all-trans retinoic acid (ATRA), 9-cis-retinoic acid (9-cRA) and 4-hydroxyphenyl retinamide (4-HPR) induce differentiation and/or apoptosis and inhibit clonal growth of acute promyelocytic leukaemia cells.	Alitretinoin	80-99	myotubularin related protein 11	Homo sapiens	103-106	
9692959-1	1998	The retinoid X receptor (RXR), a nuclear receptor that is activated by 9-cis-retinoic acid (9cRA), can regulate transcription as a homodimer or as a heterodimer with numerous other receptors.	Alitretinoin	71-90	myotubularin related protein 11	Homo sapiens	93-96	
9518882-1	1998	We investigated the effects of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and 9-cis-retinoic acid (9cRA) on parathyroid hormone-related protein (PTHrP) production and its mRNA expression by the human oral squamous carcinoma cell line (HSC-3).	Alitretinoin	74-93	myotubularin related protein 11	Homo sapiens	96-99