PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12189556-7 2002 Only pan-retinoic acid receptor and retinoic acid receptor-gamma selective agonists reduced viability and a cell line expressing very low levels of retinoic acid receptor-gamma is resistant to the effects of 9-cis-retinoic acid. Alitretinoin 208-227 retinoic acid receptor gamma Homo sapiens 148-176 11855864-3 2002 Treatment of HaCaT cells with all-trans-retinoic acid or 9-cis-retinoic acid reduced RARgamma and RXRalpha protein levels by one-half within 24 h. In contrast, retinoid treatment did not alter RARgamma or RXRalpha mRNA levels, suggesting that retinoids stimulate breakdown of their receptors. Alitretinoin 57-76 retinoic acid receptor gamma Homo sapiens 85-93 7852380-5 1995 All-trans retinoic acid, 9-cis retinoic acid, and SR11237 activated RXRE via overexpressed RXR.RXR (ED50 = 110, 120, and 11 nM, respectively), indicating interconversion between retinoic acid isomers, whereas co-overexpression of RAR alpha or RAR gamma suppressed this activation. Alitretinoin 25-44 retinoic acid receptor gamma Homo sapiens 243-252