PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29885283-10	2018	9-cis-retinoic acid weakened the sumoylation of RXRalpha, which promotes the cytoplasmic location of RXRalpha and lightens the interaction of RXRalpha and RARalpha.	Alitretinoin	0-19	retinoic acid receptor, alpha	Mus musculus	155-163	
9187263-10	1997	Using various RAR- and RXR-specific analogs and antagonists, it was demonstrated that stimulation of RAR alpha inhibits the RARgamma-specific death pathway (which explains the lack of apoptosis stimulatory effects of all-trans retinoic acid at physiological concentrations) and that costimulation of the RXR receptors (in the case of 9-cis retinoic acid) can neutralize this inhibitory effect.	Alitretinoin	334-353	retinoic acid receptor, alpha	Mus musculus	101-110	
9077482-3	1997	In cultured keratinocytes, 9-cis retinoic acid (9cRA), a panagonist for RXR and retinoic acid receptor (RAR), and an RXR-selective agonist, SR11237, synergized with D3 to activate DR3 via endogenous as well as overexpressed VDR-RXR, whereas both of these RXR agonists alone were ineffective.	Alitretinoin	27-46	retinoic acid receptor, alpha	Mus musculus	80-102	
8206989-2	1994	Both 9-cis-retinoic acid (RA) and all-trans-RA (t-RA) compete for [3H]9-cis-RA binding to RA receptors (RAR alpha, beta, and gamma) in nucleosol fractions from transiently transfected COS-1 cells with IC50 values of approximately 12 and 5 nM, respectively.	Alitretinoin	5-24	retinoic acid receptor, alpha	Mus musculus	104-113	
8206989-2	1994	Both 9-cis-retinoic acid (RA) and all-trans-RA (t-RA) compete for [3H]9-cis-RA binding to RA receptors (RAR alpha, beta, and gamma) in nucleosol fractions from transiently transfected COS-1 cells with IC50 values of approximately 12 and 5 nM, respectively.	Alitretinoin	26-28	retinoic acid receptor, alpha	Mus musculus	104-113	
8206989-2	1994	Both 9-cis-retinoic acid (RA) and all-trans-RA (t-RA) compete for [3H]9-cis-RA binding to RA receptors (RAR alpha, beta, and gamma) in nucleosol fractions from transiently transfected COS-1 cells with IC50 values of approximately 12 and 5 nM, respectively.	Alitretinoin	44-46	retinoic acid receptor, alpha	Mus musculus	104-113	
8206989-2	1994	Both 9-cis-retinoic acid (RA) and all-trans-RA (t-RA) compete for [3H]9-cis-RA binding to RA receptors (RAR alpha, beta, and gamma) in nucleosol fractions from transiently transfected COS-1 cells with IC50 values of approximately 12 and 5 nM, respectively.	Alitretinoin	44-46	retinoic acid receptor, alpha	Mus musculus	104-113	
8206989-3	1994	Curiously, 9-cis-RA competes for [3H]t-RA binding to mouse RAR alpha, beta, and gamma with IC50 values of 31, 8, and 60 nM, respectively, while t-RA itself does not exhibit such differential competition (IC50 values for RARs, 5 nM).	Alitretinoin	17-19	retinoic acid receptor, alpha	Mus musculus	59-68	
8206989-3	1994	Curiously, 9-cis-RA competes for [3H]t-RA binding to mouse RAR alpha, beta, and gamma with IC50 values of 31, 8, and 60 nM, respectively, while t-RA itself does not exhibit such differential competition (IC50 values for RARs, 5 nM).	Alitretinoin	39-41	retinoic acid receptor, alpha	Mus musculus	59-68