PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8846618-2	1995	The selective serotonin reuptake inhibitors (SSRIs) and venlafaxine display the following rank order of in vitro potency against the cytochrome P450 (CYP) isoenzyme CYP2D6 as measured by their inhibition sparteine and/or dextromethorphan metabolism: paroxetine > fluoxetine identical to norfluoxetine > or = sertraline > or = fluvoxamine > venlafaxine.	Venlafaxine Hydrochloride	56-67	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	133-148	
8846618-2	1995	The selective serotonin reuptake inhibitors (SSRIs) and venlafaxine display the following rank order of in vitro potency against the cytochrome P450 (CYP) isoenzyme CYP2D6 as measured by their inhibition sparteine and/or dextromethorphan metabolism: paroxetine > fluoxetine identical to norfluoxetine > or = sertraline > or = fluvoxamine > venlafaxine.	Venlafaxine Hydrochloride	352-363	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	133-148	
8846618-2	1995	The selective serotonin reuptake inhibitors (SSRIs) and venlafaxine display the following rank order of in vitro potency against the cytochrome P450 (CYP) isoenzyme CYP2D6 as measured by their inhibition sparteine and/or dextromethorphan metabolism: paroxetine > fluoxetine identical to norfluoxetine > or = sertraline > or = fluvoxamine > venlafaxine.	Venlafaxine Hydrochloride	352-363	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	150-153	
8846618-2	1995	The selective serotonin reuptake inhibitors (SSRIs) and venlafaxine display the following rank order of in vitro potency against the cytochrome P450 (CYP) isoenzyme CYP2D6 as measured by their inhibition sparteine and/or dextromethorphan metabolism: paroxetine > fluoxetine identical to norfluoxetine > or = sertraline > or = fluvoxamine > venlafaxine.	Venlafaxine Hydrochloride	56-67	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	150-153	
27101231-1	2016	Objectives: To determine relations between drug concentrations and the cytochrome P450-CYP2D6 genotype or phenotype among elderly patients treated with nortriptyline or venlafaxine.	Venlafaxine Hydrochloride	169-180	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	71-93	
11084219-1	2000	The present study was designed to determine the effect of venlafaxine on imipramine metabolism in an attempt to elucidate the potential for cytochrome P450 drug-drug interactions with venlafaxine.	Venlafaxine Hydrochloride	184-195	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	140-155	
19629022-6	2009	CONCLUSIONS: Considering in vitro and available clinical data, desvenlafaxine and venlafaxine appear to have low potential for pharmacokinetic drug-drug interactions via inhibiting the metabolic clearance of concomitant drugs that are substrates of various CYP enzymes, in particular CYP2D6.	Venlafaxine Hydrochloride	66-77	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	257-260	
11516890-3	2001	Although metabolized by the cytochrome P-450 (CYP) system, venlafaxine inhibits CYP 2D6 and 3A4 to a far lesser extent than do the SSRIs.	Venlafaxine Hydrochloride	59-70	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	46-49	
11098412-4	2000	Based on these parameters, selecting an antidepressant medication, such as venlafaxine, that has a low potential for drug interactions at the Cytochrome P450 (CYP) enzyme system, and is easy to monitor and dose, facilitate successful treatment of patients.	Venlafaxine Hydrochloride	75-86	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	142-157	
11098412-4	2000	Based on these parameters, selecting an antidepressant medication, such as venlafaxine, that has a low potential for drug interactions at the Cytochrome P450 (CYP) enzyme system, and is easy to monitor and dose, facilitate successful treatment of patients.	Venlafaxine Hydrochloride	75-86	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	159-162