PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33710861-8 2021 At the molecular level, Olmesartan inhibits the elevated expression of senescence biomarkers (p16 and p21). olmesartan 24-34 H3 histone pseudogene 16 Homo sapiens 102-105 33710861-11 2021 In conclusion, Olmesartan prevents oligomerized Abeta-induced cellular senescence in neuronal cells by downregulating p16 and p21 through a SIRT1 dependent deacetylation of p53; our finding indicates that Olmesartan has a protective effect in Abeta-induced neurotoxicity. olmesartan 15-25 H3 histone pseudogene 16 Homo sapiens 126-129