PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22695893-2 2012 We investigated the association of SLCO1B1, SLCO1B3 and ABCC2 polymorphisms with the pharmacokinetics of olmesartan. olmesartan 105-115 ATP binding cassette subfamily C member 2 Homo sapiens 56-61 17823233-8 2007 ATP-dependent transport into membrane vesicles expressing human MRP2 and MRP4 was clearly observed, with K(m) values of 14.9 and 26.2 microM, respectively, whereas the urinary excretion of olmesartan in Mrp4-knockout mice was not different from that of control mice. olmesartan 189-199 ATP binding cassette subfamily C member 2 Homo sapiens 64-68 22494992-0 2012 Influence of ABCC2, SLCO1B1, and ABCG2 polymorphisms on the pharmacokinetics of olmesartan. olmesartan 80-90 ATP binding cassette subfamily C member 2 Homo sapiens 13-18 22494992-1 2012 This study was designed to determine whether genetic polymorphisms of multidrug-resistant protein 2 (ABCC2), organic anion transporting polypeptide 1B1 (SLCO1B1), and breast cancer resistance protein (ABCG2) have an effect on olmesartan pharmacokinetics in Korean subjects. olmesartan 226-236 ATP binding cassette subfamily C member 2 Homo sapiens 101-106 22494992-8 2012 The ABCC2 -24CC genotype group exhibited lower systemic exposure of olmesartan than the -24CT genotype group, whereas no significant differences were observed in the other transporter genotype groups. olmesartan 68-78 ATP binding cassette subfamily C member 2 Homo sapiens 4-9 20222053-9 2010 None of the compounds tested induced mRNA transcription of P-gp or BCRP but eprosartan and olmesartan induced MRP2 mRNA expression. olmesartan 91-101 ATP binding cassette subfamily C member 2 Homo sapiens 110-114 17823233-10 2007 Vectorial basal-to-apical transport was observed in OATP1B1/MRP2, OATP1B1/MDR1 double, and OATP1B1/BCRP double transfectants, suggesting the possible involvement of MRP2, MDR1, and BCRP in the limit of intestinal absorption of olmesartan medoxomil. olmesartan 227-237 ATP binding cassette subfamily C member 2 Homo sapiens 165-169 16501004-0 2006 OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker. olmesartan 70-80 ATP binding cassette subfamily C member 2 Homo sapiens 22-26 16501004-7 2006 ATP-dependent uptake of olmesartan was observed in both human canalicular membrane vesicles (hCMVs) and MRP2-expressing vesicles. olmesartan 24-34 ATP binding cassette subfamily C member 2 Homo sapiens 104-108