PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35563469-7	2022	Results: We report here that EMD, like the inflammasome (NLRP3) and CAS1 specific inhibitors-MCC950 and Ac-YVAD-cmk, respectively-lowered the LPS-induced expression of NLRP3 in primary macrophages (EMD: p = 0.0232; MCC950: p = 0.0426; Ac-YVAD-cmk: p = 0.0317).	ac-yvad	104-111	NLR family, pyrin domain containing 3	Mus musculus	168-173	
28482444-10	2017	After stimulated by Pg LPS, mRNA and protein expression of IL-1beta (P<0.01, P<0.01) and NALP3 (P<0.01, P<0.01) significantly increased; but the expression of IL-1beta (P=0.002, P=0.027) and NALP3 (P<0.01, P<0.01) were decreased when pretreated with AC-YVAD-CMK.	ac-yvad	268-275	NLR family, pyrin domain containing 3	Mus musculus	95-100	
30276509-9	2019	In addition, administration of MCC950 or Ac-YVAD-CMK rescues cognitive deficits and ameliorates increased hippocampal NLRP3-mediated neuronal pyroptosis and pro-inflammatory cytokines.	ac-yvad	41-48	NLR family, pyrin domain containing 3	Mus musculus	118-123	
27053298-9	2016	Overall, our results showed that the caspase-1 inhibitor AC-YVAD-CMK protected against acute gastric injury in mice by affecting the NLRP3 inflammasome and attenuating inflammatory processes and apoptosis.	ac-yvad	57-64	NLR family, pyrin domain containing 3	Mus musculus	133-138	
27053298-0	2016	The caspase-1 inhibitor AC-YVAD-CMK attenuates acute gastric injury in mice: involvement of silencing NLRP3 inflammasome activities.	ac-yvad	24-31	NLR family, pyrin domain containing 3	Mus musculus	102-107	
24279434-8	2014	Pretreatment with the NLRP3 inflammasome inhibitor Ac-YVAD-CMK significantly abrogated the depressive-like behaviors induced by lipopolysaccharide.	ac-yvad	51-58	NLR family, pyrin domain containing 3	Mus musculus	22-27