PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16363885-13 2005 Biotransformation by the cytochrome P450 (CYP450) system is an important step in the activation or elimination of a large number of drugs, including oxybutynin, tolterodine, darifenacin and solifenacin, raising the possibility of clinically relevant and potentially serious drug interactions. Solifenacin Succinate 190-201 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 25-40 17489643-5 2007 Of the drugs indicated for OAB, tolterodine, darifenacin, solifenacin, and oxybutynin are extensively metabolized by CYP450, but trospium is not. Solifenacin Succinate 58-69 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 117-123 16363885-13 2005 Biotransformation by the cytochrome P450 (CYP450) system is an important step in the activation or elimination of a large number of drugs, including oxybutynin, tolterodine, darifenacin and solifenacin, raising the possibility of clinically relevant and potentially serious drug interactions. Solifenacin Succinate 190-201 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 42-48