PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28926106-0 2018 Oroxyloside inhibits angiogenesis through suppressing internalization of VEGFR2/Flk-1 in endothelial cells. oroxylin A-7-O-glucuronide 0-11 kinase insert domain receptor Homo sapiens 73-79 28926106-0 2018 Oroxyloside inhibits angiogenesis through suppressing internalization of VEGFR2/Flk-1 in endothelial cells. oroxylin A-7-O-glucuronide 0-11 kinase insert domain receptor Homo sapiens 80-85 28926106-6 2018 Mechanism studies showed that Oroxyloside reduced the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2/Flk-1) while it up-regulated the expression of R-Ras and VE-cadherin. oroxylin A-7-O-glucuronide 30-41 kinase insert domain receptor Homo sapiens 77-122 28926106-6 2018 Mechanism studies showed that Oroxyloside reduced the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2/Flk-1) while it up-regulated the expression of R-Ras and VE-cadherin. oroxylin A-7-O-glucuronide 30-41 kinase insert domain receptor Homo sapiens 124-130 28926106-6 2018 Mechanism studies showed that Oroxyloside reduced the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2/Flk-1) while it up-regulated the expression of R-Ras and VE-cadherin. oroxylin A-7-O-glucuronide 30-41 kinase insert domain receptor Homo sapiens 131-136 28926106-8 2018 Furthermore, in vivo study showed that Oroxyloside exhibited a potential anti-angiogenic effect in Matrigel plug assay and inhibited growth of xenografted tumors with low systemic toxicity, which could be ascribed to the inhibition of VEGFR2 internalization. oroxylin A-7-O-glucuronide 39-50 kinase insert domain receptor Homo sapiens 235-241 28926106-9 2018 Taken together, these results suggested that Oroxyloside could inhibit angiogenesis in vitro and in vivo via suppressing the internalization of VEGFR2 and might serve as a potential antitumor agent. oroxylin A-7-O-glucuronide 45-56 kinase insert domain receptor Homo sapiens 144-150