PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12589938-2 2002 The chalcone isoliquiritigenin (ISL) is a component of licorice extract exhibiting either antitumorigenic activity or estrogen receptor (ER) alpha-dependent growth promoting effects on breast cancer cells. isoliquiritigenin 32-35 estrogen receptor 1 Homo sapiens 118-146 11595510-4 2001 Results indicated that glabrene and isoliquiritigenin, (2",4",4-three hydroxy chalcone) (ILC) in the licorice extract can bind to the human ER with higher affinity (IC50, 1 and 0.5 microM) than glabridin (IC50, 5 microM). isoliquiritigenin 36-53 estrogen receptor 1 Homo sapiens 140-142