PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27133739-1 2016 The present in vitro experiments demonstrate inhibitory effects of polysubstituted 2-aminopyrimidines on high output production of nitric oxide (NO) and prostaglandin E2 (PGE2) stimulated by interferon-gamma and lipopolysaccharide (LPS) in peritoneal macrophages of mouse and rat origin. 2-aminopyrimidine 83-101 interferon gamma Mus musculus 191-207