PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27549813-1 2016 Here is reported the development of a novel scoring function that performs remarkably well at identifying the native binding pose of a subset of HSP90 inhibitors containing aminopyrimidine or resorcinol based scaffolds. 2-aminopyrimidine 173-188 heat shock protein 90 alpha family class A member 1 Homo sapiens 145-150 27549813-5 2016 These results indicate that the specific residues considered by PocketScore are determinant to properly model the interaction between HSP90 and its subset of inhibitors containing aminopyrimidine or resorcinol based scaffolds. 2-aminopyrimidine 180-195 heat shock protein 90 alpha family class A member 1 Homo sapiens 134-139 21875802-4 2011 This approach quickly identified 2-aminotriazine and 2-aminopyrimidine derivatives as specific ligands to Hsp90 with high ligand efficiency. 2-aminopyrimidine 53-70 heat shock protein 90 alpha family class A member 1 Homo sapiens 106-111