PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20385788-2 2010 We have identified an aminopyrimidine derivative (CYT387), which inhibits JAK1, JAK2, and tyrosine kinase 2 (TYK2) at low nanomolar concentrations, with few additional targets. 2-aminopyrimidine 22-37 Janus kinase 1 Mus musculus 74-78