PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10400908-0	1999	Opposing effects of reactive oxygen species and cholesterol on endothelial nitric oxide synthase and endothelial cell caveolae.	Cholesterol	48-59	nitric oxide synthase 3	Bos taurus	63-96	
10400908-6	1999	Treatment of BAECs with 30 microgram/mL cholesterol for 24 hours stimulated significant increases in total eNOS protein expression (1.50-fold), eNOS associated with caveolae-enriched membranes (2.23-fold), and calcium ionophore-stimulated NO production (1.56-fold).	Cholesterol	40-51	nitric oxide synthase 3	Bos taurus	107-111	
10400908-6	1999	Treatment of BAECs with 30 microgram/mL cholesterol for 24 hours stimulated significant increases in total eNOS protein expression (1.50-fold), eNOS associated with caveolae-enriched membranes (2.23-fold), and calcium ionophore-stimulated NO production (1.56-fold).	Cholesterol	40-51	nitric oxide synthase 3	Bos taurus	144-148	
10400908-8	1999	Treatment of BAECs for 24 hours with 1 micromol/L LY83583, a superoxide-generating napthoquinolinedione, decreased caveolae number measured by electron microscopy and prevented the cholesterol-mediated increases in eNOS expression.	Cholesterol	181-192	nitric oxide synthase 3	Bos taurus	215-219	
10400908-10	1999	These results show that cholesterol treatment increases eNOS expression, whereas ROS treatment decreases eNOS expression and the association of eNOS with caveolin in caveolae-enriched membranes.	Cholesterol	24-35	nitric oxide synthase 3	Bos taurus	56-60	
17028163-8	2007	Perturbation of membrane raft structural integrity with cholesterol-sequestering compounds caused the delocalization of NADPH oxidase subunits and eNOS from the rafts and inhibited TNF-alpha-induced ROS production and protein tyrosine nitration.	Cholesterol	56-67	nitric oxide synthase 3	Bos taurus	147-151	
15383526-0	2004	Cyclosporin A inhibits flow-mediated activation of endothelial nitric-oxide synthase by altering cholesterol content in caveolae.	Cholesterol	97-108	nitric oxide synthase 3	Bos taurus	51-84