PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18585453-2 2008 The abilities of recombinant human PON1 and PON3 to retard LDL oxidation, prevent macrophage oxidative stress, and promote macrophage cholesterol efflux were investigated. Cholesterol 134-145 paraoxonase 3 Homo sapiens 44-48 18585453-5 2008 PON3 promoted macrophage cholesterol efflux (30% at 40 microg/ml, P<0.01); however, PON1 was found to be cytotoxic to the macrophages derived from the human monocyte THP-1 cell line. Cholesterol 25-36 paraoxonase 3 Homo sapiens 0-4 15098021-3 2004 PON1 and PON3 reside on high-density lipoprotein (HDL, "good cholesterol") and are involved in the prevention of atherosclerosis. Cholesterol 61-72 paraoxonase 3 Homo sapiens 9-13 33128247-6 2021 RESULTS: We found consistent differences in two proteins involved in cholesterol homeostasis; significantly increased proprotein convertase subtilisin/kexin type 9 (PCSK9) (p<0.05) and significantly decreased paraoxonase 3 (PON3) (p<0.05). Cholesterol 69-80 paraoxonase 3 Homo sapiens 209-222 33128247-6 2021 RESULTS: We found consistent differences in two proteins involved in cholesterol homeostasis; significantly increased proprotein convertase subtilisin/kexin type 9 (PCSK9) (p<0.05) and significantly decreased paraoxonase 3 (PON3) (p<0.05). Cholesterol 69-80 paraoxonase 3 Homo sapiens 224-228 33128247-8 2021 CONCLUSIONS: We identified consistent changes in two proteins involved in cholesterol homeostasis which may be important players in the pathogenesis of CAV: PON3 and PCSK9. Cholesterol 74-85 paraoxonase 3 Homo sapiens 157-161 20182519-8 2010 Although no synergistic mechanism was detected in reducing arterial lesion size, hPON1 and hPON3 showed synergistic effects on promoting macrophage cholesterol efflux. Cholesterol 148-159 paraoxonase 3 Homo sapiens 91-96 17913690-2 2007 PON1 and PON3 reside on high-density lipoprotein (HDL) (the "good cholesterol"), and are involved in the alleviation of atherosclerosis. Cholesterol 66-77 paraoxonase 3 Homo sapiens 9-13