PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26109739-1 2015 OBJECTIVE: We previously demonstrated that subjects with functional ATP-binding cassette (ABC) A1 mutations have increased atherosclerosis, which has been attributed to the role of ABCA1 in reverse cholesterol transport. Cholesterol 198-209 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 68-88 25976863-0 2015 Association of ABC (HbA1c, blood pressure, LDL-cholesterol) goal attainment with depression and health-related quality of life among adults with type 2 diabetes. Cholesterol 47-58 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 15-18 26109739-1 2015 OBJECTIVE: We previously demonstrated that subjects with functional ATP-binding cassette (ABC) A1 mutations have increased atherosclerosis, which has been attributed to the role of ABCA1 in reverse cholesterol transport. Cholesterol 198-209 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 90-93 23983199-7 2013 Recently, several ATP-binding cassette (ABC) transporters, such as ABCA1, ABCG1, ABCG5, and ABCG8 have been shown to play important roles in the regulation of cellular cholesterol homeostasis by mediating cholesterol efflux. Cholesterol 168-179 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 18-38 25737034-0 2015 Comparison of HbA1c, blood pressure, and cholesterol (ABC) control in type 2 diabetes attending general medical clinics and specialist diabetes clinics in Thailand. Cholesterol 41-52 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 54-57 24105869-3 2014 In the liver, ABC transporters are involved in diverse physiological processes including export of cholesterol, bile salts, and metabolic endproducts. Cholesterol 99-110 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 14-17 25418064-11 2015 Clinically, pharmacological modulation of the activity of selected intrafollicular ABC transporters may permit novel therapeutic interventions, such as protecting HF stem cells from chemotherapy-induced damage, counteracting cholesterol-associated hypertrichosis, and manipulating the intrafollicular prostaglandin balance in androgenetic alopecia. Cholesterol 225-236 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 83-86 24252657-2 2014 ATP-binding cassette (ABC) transporters G5 (ABCG5) and G8 (ABCG8) form an obligate heterodimer that limits intestinal absorption and facilitates biliary secretion of cholesterol and phytosterols. Cholesterol 166-177 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-20 24252657-2 2014 ATP-binding cassette (ABC) transporters G5 (ABCG5) and G8 (ABCG8) form an obligate heterodimer that limits intestinal absorption and facilitates biliary secretion of cholesterol and phytosterols. Cholesterol 166-177 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 22-25 23983199-9 2013 In this review, we discuss the physiological roles of ABC transporters and the underlying mechanisms by which they mediate cholesterol translocation. Cholesterol 123-134 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 54-57 23625363-7 2013 Recently, several ATP-binding cassette (ABC) transporters, such as ABCA1, ABCG1, ABCG5, and ABCG8 have been shown to play important roles in the regulation of cellular cholesterol homeostasis by mediating cholesterol efflux. Cholesterol 168-179 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 18-38 23625363-7 2013 Recently, several ATP-binding cassette (ABC) transporters, such as ABCA1, ABCG1, ABCG5, and ABCG8 have been shown to play important roles in the regulation of cellular cholesterol homeostasis by mediating cholesterol efflux. Cholesterol 168-179 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 40-43 23625363-7 2013 Recently, several ATP-binding cassette (ABC) transporters, such as ABCA1, ABCG1, ABCG5, and ABCG8 have been shown to play important roles in the regulation of cellular cholesterol homeostasis by mediating cholesterol efflux. Cholesterol 205-216 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 18-38 23625363-7 2013 Recently, several ATP-binding cassette (ABC) transporters, such as ABCA1, ABCG1, ABCG5, and ABCG8 have been shown to play important roles in the regulation of cellular cholesterol homeostasis by mediating cholesterol efflux. Cholesterol 205-216 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 40-43 23625363-9 2013 In this review, we discuss the physiological roles of ABC transporters and the underlying mechanisms by which they mediate cholesterol translocation. Cholesterol 123-134 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 54-57 23983199-7 2013 Recently, several ATP-binding cassette (ABC) transporters, such as ABCA1, ABCG1, ABCG5, and ABCG8 have been shown to play important roles in the regulation of cellular cholesterol homeostasis by mediating cholesterol efflux. Cholesterol 168-179 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 40-43 23983199-7 2013 Recently, several ATP-binding cassette (ABC) transporters, such as ABCA1, ABCG1, ABCG5, and ABCG8 have been shown to play important roles in the regulation of cellular cholesterol homeostasis by mediating cholesterol efflux. Cholesterol 205-216 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 18-38 23983199-7 2013 Recently, several ATP-binding cassette (ABC) transporters, such as ABCA1, ABCG1, ABCG5, and ABCG8 have been shown to play important roles in the regulation of cellular cholesterol homeostasis by mediating cholesterol efflux. Cholesterol 205-216 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 40-43 23181169-5 2012 Recent studies have unraveled important roles of ABC transporters including ABCB1 (P-glycoprotein, P-gp), ABCG2 (breast cancer resistant protein, BCRP), ABCC1 (multidrug resistance protein 1, MRP1), and the cholesterol transporter ABCA1 in the pathogenesis of AD and Abeta peptides deposition inside the brain. Cholesterol 207-218 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 49-52 23139370-2 2012 Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Cholesterol 44-55 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 72-92 23139370-2 2012 Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Cholesterol 44-55 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 94-97 19530968-0 2009 Impact of cholesterol on ABC and SLC transporters expression and function and its role in disposition variability to lipid-lowering drugs. Cholesterol 10-21 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 25-28 21967049-7 2011 The chapter also emphasizes that some ABC transporters, although important for elimination of toxic compounds (xenobiotics), are also increasingly seen to play crucial roles in homoeostatic regulation of membrane biogenesis and function through translocation of endogenous allocrites such as cholesterol. Cholesterol 292-303 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 38-41 21534641-0 2011 Prevalence of achievement of A1c, blood pressure, and cholesterol (ABC) goal in veterans with diabetes. Cholesterol 54-65 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 67-70 21389634-5 2011 ABCA1, an ABC protein, eliminates excess cholesterol in peripheral cells by generating HDL. Cholesterol 41-52 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-3 19426719-2 2009 Most ABC transporters localize to the plasma membrane; some are associated with liquid-ordered cholesterol-/sphingolipid-rich microdomains, and to a lesser extent the membranes of the Golgi and endoplasmic reticulum. Cholesterol 95-106 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 5-8 19426719-6 2009 Cholesterol, a major membrane microdomain component, is not only a substrate of several ABC transporters, but also regulates ABC activity through its effects on microdomain structure. Cholesterol 0-11 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 88-91 19426719-6 2009 Cholesterol, a major membrane microdomain component, is not only a substrate of several ABC transporters, but also regulates ABC activity through its effects on microdomain structure. Cholesterol 0-11 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 125-128 18700997-3 2008 Based on findings in the context of human disorders we speculated that candidate ABC transporters are implicated in lipid and cholesterol transport in the mammary gland. Cholesterol 126-137 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 81-84 18700997-9 2008 These results indicate that candidate ABC transporters involved in lipid and cholesterol transport show differential mRNA expression between lactation and the dry period. Cholesterol 77-88 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 38-41 17955353-0 2007 Cholesterol fill-in model: mechanism for substrate recognition by ABC proteins. Cholesterol 0-11 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 66-69 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 214-225 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 70-73 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 214-225 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 103-106 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 214-225 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 103-106 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 240-251 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 70-73 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 240-251 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 103-106 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 240-251 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 103-106 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 257-268 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 70-73 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 257-268 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 103-106 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 257-268 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 103-106 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 240-251 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 70-73 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 240-251 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 103-106 17955353-3 2007 We compared the functions of drug-transporting and lipid-transporting ABC proteins, and found that (1) ABC proteins, either lipid or drug transporters, have a similar substrate binding site which recognizes PL and cholesterol, or drugs and cholesterol; (2) Cholesterol in membranes binds to various ABC proteins together with PL or drugs, and plays an important role in substrate recognition, especially by ABCB1/MDR1, where cholesterol fills the empty space in the substrate binding site when small drugs bind to it. Cholesterol 240-251 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 103-106 14529830-7 2003 Our data demonstrate that gene transfer-mediated expression of human apoA-I in macrophages can compensate in part for apoE deficiency and delay the progression of atherosclerotic lesions by stimulating ABC-dependent cholesterol efflux and RCT. Cholesterol 216-227 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 202-205 16187691-3 2005 Recent data regarding how these ABC transporters control cholesterol and phospholipid homeostasis have provided valuable insights into the mechanisms of mRNA and protein expression, intracellular trafficking, surface membrane localization and interaction with binding partners and lipoproteins. Cholesterol 57-68 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 32-35 16399363-2 2005 Mutations in ABC transporters cause or contribute to a number of different Mendelian disorders, including adrenoleukodystrophy, cystic fibrosis, retinal degeneration, cholesterol, and bile transport defects. Cholesterol 167-178 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 13-16 17690481-0 2007 Cholesterol and plant sterol efflux from cultured intestinal epithelial cells is mediated by ATP-binding cassette transporters. Cholesterol 0-11 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 93-113 17690481-3 2007 The ligand stimulated cholesterol efflux, suggesting that ABC transporters are involved in it. Cholesterol 22-33 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 58-61 17900061-4 2007 Mutations in ABC transporters are implicated in a number of Mendelian disorders such as cystic fibrosis, adrenoleukodystrophy and cholesterol and bile transport defects. Cholesterol 130-141 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 13-16 15342687-12 2004 Cholesterol flux regulates ABC expression but not NPC1L1. Cholesterol 0-11 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 27-30 15053163-4 2004 DATA SYNTHESIS: Nuclear hormone receptors, such as the liver X, farnesoid X and retinoid X receptors, regulate the absorption of dietary sterols by modulating the transcription of several genes involved in cholesterol metabolism, The ABC proteins transport dietary cholesterol from enterocytes back to the intestinal lumen, thus limiting the amount of absorbed cholesterol. Cholesterol 206-217 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 234-237 15053163-4 2004 DATA SYNTHESIS: Nuclear hormone receptors, such as the liver X, farnesoid X and retinoid X receptors, regulate the absorption of dietary sterols by modulating the transcription of several genes involved in cholesterol metabolism, The ABC proteins transport dietary cholesterol from enterocytes back to the intestinal lumen, thus limiting the amount of absorbed cholesterol. Cholesterol 265-276 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 234-237 15053163-4 2004 DATA SYNTHESIS: Nuclear hormone receptors, such as the liver X, farnesoid X and retinoid X receptors, regulate the absorption of dietary sterols by modulating the transcription of several genes involved in cholesterol metabolism, The ABC proteins transport dietary cholesterol from enterocytes back to the intestinal lumen, thus limiting the amount of absorbed cholesterol. Cholesterol 265-276 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 234-237 12509503-0 2003 Role of ABC transporters in secretion of cholesterol from liver into bile. Cholesterol 41-52 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 8-11 12773300-2 2003 We previously reported that ATP binding cassette (ABC)A1 mediates basolateral (BL) cholesterol efflux in cultured polarized GBEC. Cholesterol 83-94 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 50-53 12925201-3 2003 To test the hypothesis that ABC molecules are potentially involved in the epidermal transport of sphingolipids, glycerophospholipids, cholesterol, and fatty acids, we performed mRNA expression profiling of all currently known ABC molecules during in vitro differentiation of human keratinocytes and HaCaT cells. Cholesterol 134-145 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 28-31 34829614-2 2021 ATP-binding cassette (ABC) transporters mediate cholesterol transfer across the placenta and enhance cell survival by effluxing substrates from target cells in the presence of stressors. Cholesterol 48-59 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-20 11099417-0 2000 Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Cholesterol 24-35 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 86-89 12363033-2 2002 The prototypic ABC transporter ABCA1 has recently been demonstrated to act as a major facilitator of cellular cholesterol and phospholipid export. Cholesterol 110-121 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 15-18 11229879-4 2001 Expression of a large number of ABC transporters in monocytes/macrophages and their regulation by cholesterol flux render these transporter molecules potentially critical players in chronic inflammatory diseases such as atherosclerosis. Cholesterol 98-109 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 32-35 10725792-7 1999 In a comprehensive analysis of the expression and regulation of all currently known human ABC transporters, we identified additional cholesterol-responsive genes that are induced during monocyte differentiation into macrophages. Cholesterol 133-144 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 90-93 34829614-2 2021 ATP-binding cassette (ABC) transporters mediate cholesterol transfer across the placenta and enhance cell survival by effluxing substrates from target cells in the presence of stressors. Cholesterol 48-59 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 22-25 35124425-2 2022 Cholesterol and sterol transport is a key function of the placenta and it is elicited through ATP binding cassette (ABC) transporters. Cholesterol 0-11 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 116-119 34404721-1 2021 The ABCG1 homodimer (G1) and ABCG5-ABCG8 heterodimer (G5G8), two members of the adenosine triphosphate (ATP)-binding cassette (ABC) transporter G family, are required for maintenance of cellular cholesterol levels. Cholesterol 195-206 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 127-130 34404721-8 2021 These structures, along with functional validation studies, provide a mechanistic framework for understanding cholesterol efflux via ABC transporters. Cholesterol 110-121 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 133-136 34362211-1 2021 ABC (glucose, blood pressure and LDL-cholesterol) goals are basic standards of diabetes care. Cholesterol 37-48 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-3 33141631-4 2021 Biochemical and structural information on ABC sterol transporters is beginning to emerge, with published structures of ABCA1 and ABCG5/G8; these two proteins function in the reverse cholesterol transport pathway and mediate the efflux of cholesterol and xenosterols to high-density lipoprotein and bile-salt micelles, respectively. Cholesterol 182-193 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 42-45 35575923-5 2022 The first and rate-limiting step of RCT is ATP-binding cassette (ABC) transports A1 (ABCA1)- and ABCG1-dependent cholesterol efflux. Cholesterol 113-124 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 43-63 35575923-5 2022 The first and rate-limiting step of RCT is ATP-binding cassette (ABC) transports A1 (ABCA1)- and ABCG1-dependent cholesterol efflux. Cholesterol 113-124 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 65-68 33422548-9 2021 Treating cells with apoprotein A1 and with nuclear receptor liver X-receptor (LXR) agonists to upregulate expression of ABC transporters enhanced cholesterol efflux from the PM, at least partly by accelerating vesicle release. Cholesterol 146-157 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 120-123 33141631-4 2021 Biochemical and structural information on ABC sterol transporters is beginning to emerge, with published structures of ABCA1 and ABCG5/G8; these two proteins function in the reverse cholesterol transport pathway and mediate the efflux of cholesterol and xenosterols to high-density lipoprotein and bile-salt micelles, respectively. Cholesterol 238-249 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 42-45 31286451-0 2020 Spotlight from the American Society for Preventive Cardiology on Key Features of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guidelines on the Management of Blood Cholesterol. Cholesterol 184-195 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 110-113 32745159-1 2020 ATP-Binding Cassette (ABC) transporters are involved in cholesterol metabolism and their dysfunctions could lead to obesity-associated complications. Cholesterol 56-67 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-20 32745159-1 2020 ATP-Binding Cassette (ABC) transporters are involved in cholesterol metabolism and their dysfunctions could lead to obesity-associated complications. Cholesterol 56-67 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 22-25 31988241-0 2020 ABC transporters control ATP release through cholesterol-dependent volume-regulated anion channel activity. Cholesterol 45-56 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-3 33546617-15 2021 In particular, the patients with two mutations in ABC family genes had higher average values of total bile acids (TBA), aspartate transaminase (AST), direct bilirubin (DBIL), total cholesterol (CHOL), triglycerides (TG) and high-density lipoprotein (HDL) than the patients who had one mutation, no mutation in ABC genes and local controls. Cholesterol 181-192 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 50-53 33002191-5 2020 ABC proteins are also assumed to have accelerated the evolution of vertebrates by allowing cholesterol to function for intra-membrane signaling. Cholesterol 91-102 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-3 32705595-14 2020 We also discuss other ABC transporters such as ABCG4, which also promotes cholesterol efflux to HDL and controls megakaryocyte proliferation and platelet biogenesis. Cholesterol 74-85 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 22-25 30565953-0 2019 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Cholesterol 98-109 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 25-28 31612028-3 2019 The role of statins in CCA cell cholesterol transport through the expression and function of ATP-binding cassette (ABC) A1 and ABCG1 was investigated in the current study. Cholesterol 32-43 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 93-113 31612028-3 2019 The role of statins in CCA cell cholesterol transport through the expression and function of ATP-binding cassette (ABC) A1 and ABCG1 was investigated in the current study. Cholesterol 32-43 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 115-118 32990606-0 2020 Association of ABC (HbA1c, blood pressure and LDL-cholesterol) goal achievement with visit-to-visit ABC variability and postprandial dysmetabolism in type 2 diabetic patients. Cholesterol 50-61 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 15-18 32990606-0 2020 Association of ABC (HbA1c, blood pressure and LDL-cholesterol) goal achievement with visit-to-visit ABC variability and postprandial dysmetabolism in type 2 diabetic patients. Cholesterol 50-61 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 100-103 30423393-0 2019 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Cholesterol 98-109 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 25-28 30423394-0 2019 Systematic Review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Cholesterol 124-135 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 51-54 31206328-0 2019 Correction to: 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Cholesterol 113-124 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 40-43 31206330-0 2019 Correction to: 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Cholesterol 113-124 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 40-43 31206332-0 2019 Correction to: Systematic Review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Cholesterol 139-150 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 66-69 30586774-0 2019 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Cholesterol 98-109 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 25-28 28383515-4 2017 Subsequently, further ABC transporters, i.e., ABCG1, ABCG4, ABCB6, ABCC1, ABCC6 or ABCC9, have been shown to directly or indirectly affect cellular cholesterol efflux, the inflammatory response in macrophages, megakaryocyte proliferation and thrombus formation, as well as vascular function and blood pressure, and may thereby contribute to the pathogenesis of CVD and its complications. Cholesterol 148-159 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 60-65 31571164-7 2019 Some ABC transporters are also involved in diverse cellular processes such as maintenance of osmotic homeostasis, antigen processing, cell division, immunity, cholesterol, and lipid trafficking. Cholesterol 159-170 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 5-8 31049145-4 2019 Although it was submitted prior to publication of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol, this review also includes key takeaway messages from the updated guideline. Cholesterol 152-163 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 79-82 28268212-3 2017 We investigated whether ceramide plays a role in cholesterol efflux through the ABC transporters. Cholesterol 49-60 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 80-83 27176141-11 2016 ABBREVIATIONS: A1c = glycated hemoglobin A1c ABC = composite of A1c, blood pressure, and cholesterol ACEi = angiotensin-converting enzyme inhibitor ARB = angiotensin receptor blocker BMI = body mass index BP = blood pressure EHR = electronic health record LDL = low-density lipoprotein NCHS = National Center for Health Statistics NHANES = National Health and Nutrition Examination Survey PCP = primary care provider. Cholesterol 89-100 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 45-48 28241820-4 2017 Three ATP-binding cassette (ABC) transporters are found in the mammalian lung - ABCA1, ABCG1 and ABCA3 - that are involved in movement of cholesterol and phospholipids from lung cells. Cholesterol 138-149 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 6-26 28241820-4 2017 Three ATP-binding cassette (ABC) transporters are found in the mammalian lung - ABCA1, ABCG1 and ABCA3 - that are involved in movement of cholesterol and phospholipids from lung cells. Cholesterol 138-149 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 28-31