PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31398058-0 2019 High-mannose intercellular adhesion molecule-1 (ICAM-1) enhances CD16+ monocyte adhesion to the endothelium. Mannose 5-12 intercellular adhesion molecule 1 Homo sapiens 13-46 32171755-4 2020 Previous data from our lab has shown that endothelial inflammation produces multiple N-glycoforms of ICAM-1, and that a hypoglycosylated, or high-mannose (HM), form of ICAM-1 enhances adhesion of pro-inflammatory monocytes associated with more severe atherosclerosis and adverse cardiac events. Mannose 146-153 intercellular adhesion molecule 1 Homo sapiens 168-174 32208424-3 2020 However, our recent studies suggest that hypoglycosylated or high mannose (HM)-ICAM-1 N-glycoforms are also expressed on the cell surface during endothelial dysfunction, and have higher affinity for monocyte adhesion and regulate outside-in endothelial signaling by different mechanisms. Mannose 66-73 intercellular adhesion molecule 1 Homo sapiens 79-85 31398058-0 2019 High-mannose intercellular adhesion molecule-1 (ICAM-1) enhances CD16+ monocyte adhesion to the endothelium. Mannose 5-12 intercellular adhesion molecule 1 Homo sapiens 48-54 31398058-4 2019 Here, we tested the hypothesis that a high mannose (HM) N-glycoform of intercellular adhesion molecule-1 (ICAM-1) on the endothelium mediates the selective recruitment of CD16+ monocytes. Mannose 43-50 intercellular adhesion molecule 1 Homo sapiens 71-104 31398058-4 2019 Here, we tested the hypothesis that a high mannose (HM) N-glycoform of intercellular adhesion molecule-1 (ICAM-1) on the endothelium mediates the selective recruitment of CD16+ monocytes. Mannose 43-50 intercellular adhesion molecule 1 Homo sapiens 106-112 22271390-0 2012 Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation. Mannose 98-105 intercellular adhesion molecule 1 Homo sapiens 32-65 23703526-0 2013 Identification of a high-mannose ICAM-1 glycoform: effects of ICAM-1 hypoglycosylation on monocyte adhesion and outside in signaling. Mannose 25-32 intercellular adhesion molecule 1 Homo sapiens 33-39 23703526-5 2013 Production of exclusively HM-ICAM-1 in cells by alpha-mannosidase inhibition increased monocyte rolling and adhesion compared with mature ICAM-1 consistent with high-mannose epitopes providing leukocyte ligands. Mannose 166-173 intercellular adhesion molecule 1 Homo sapiens 29-35 24649404-0 2014 Ursolic acid, a natural pentacyclic triterpenoid, inhibits intracellular trafficking of proteins and induces accumulation of intercellular adhesion molecule-1 linked to high-mannose-type glycans in the endoplasmic reticulum. Mannose 174-181 intercellular adhesion molecule 1 Homo sapiens 125-158 24649404-7 2014 Ursolic acid induced the accumulation of ICAM-1 in the endoplasmic reticulum, which was linked mainly to high-mannose-type glycans. Mannose 110-117 intercellular adhesion molecule 1 Homo sapiens 41-47 24649404-9 2014 Thus, our results reveal that ursolic acid inhibits intracellular trafficking of proteins and induces the accumulation of ICAM-1 linked to high-mannose-type glycans in the endoplasmic reticulum. Mannose 144-151 intercellular adhesion molecule 1 Homo sapiens 122-128 22271390-4 2012 Here, we developed an ICAM-1 small interfering RNA (siRNA) transfer method using ultrasound (US)-responsive and mannose-modified liposome/ICAM-1 siRNA complexes (Man-PEG(2000) bubble lipoplexes [Man-PEG(2000) BLs]), and achieved efficient HEC-selective ICAM-1 siRNA delivery in combination with US exposure. Mannose 112-119 intercellular adhesion molecule 1 Homo sapiens 22-28 22271390-4 2012 Here, we developed an ICAM-1 small interfering RNA (siRNA) transfer method using ultrasound (US)-responsive and mannose-modified liposome/ICAM-1 siRNA complexes (Man-PEG(2000) bubble lipoplexes [Man-PEG(2000) BLs]), and achieved efficient HEC-selective ICAM-1 siRNA delivery in combination with US exposure. Mannose 112-119 intercellular adhesion molecule 1 Homo sapiens 138-144 22271390-4 2012 Here, we developed an ICAM-1 small interfering RNA (siRNA) transfer method using ultrasound (US)-responsive and mannose-modified liposome/ICAM-1 siRNA complexes (Man-PEG(2000) bubble lipoplexes [Man-PEG(2000) BLs]), and achieved efficient HEC-selective ICAM-1 siRNA delivery in combination with US exposure. Mannose 112-119 intercellular adhesion molecule 1 Homo sapiens 138-144 19733219-7 2009 In contrast, high-mannose-type N-glycans and Lewis X were more commonly found in rat brain ICAM-5 than in human ICAM-1 expressed in CHO cells, HEK cells, or mouse myeloma cells and ICAM-3 isolated from human T-cells. Mannose 18-25 intercellular adhesion molecule 1 Homo sapiens 112-118 22496445-6 2012 Mannose supplementation of phosphomannose isomerase-deficient CDG-Ib (MPI-CDG) cells and complementation with PMM2 in PMM2-deficient CDG-Ia (PMM2-CDG) cells partially corrected hypoglycosylation based on increased ICAM-1 presence on the plasma membrane. Mannose 0-7 intercellular adhesion molecule 1 Homo sapiens 214-220 15545280-7 2005 High mannose glycans were absent in ICAM-1, which did not bind to the lectin, but they appeared in ICAM-1 mutants with additional N-linked glycosylation and lectin binding activity. Mannose 5-12 intercellular adhesion molecule 1 Homo sapiens 36-42 15545280-7 2005 High mannose glycans were absent in ICAM-1, which did not bind to the lectin, but they appeared in ICAM-1 mutants with additional N-linked glycosylation and lectin binding activity. Mannose 5-12 intercellular adhesion molecule 1 Homo sapiens 99-105