PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33401221-0	2021	d-Mannose suppresses osteoarthritis development in vivo and delays IL-1beta-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.	Mannose	0-9	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	147-151	
33401221-6	2021	In terms of a downstream mechanism, we showed that d-mannose might attenuate OA degeneration by activating autophagy in IL-1beta-treated rat chondrocytes by promoting the phosphorylation of 5" AMP-activated protein kinase (AMPK).	Mannose	51-60	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	223-227	
33401221-7	2021	Our in vitro findings revealed that d-mannose delayed IL-1beta-induced OA degeneration in rat chondrocytes by enhancing autophagy activation through the AMPK pathway.	Mannose	36-45	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	153-157	
33401221-6	2021	In terms of a downstream mechanism, we showed that d-mannose might attenuate OA degeneration by activating autophagy in IL-1beta-treated rat chondrocytes by promoting the phosphorylation of 5" AMP-activated protein kinase (AMPK).	Mannose	51-60	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	193-221