PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23472095-9 2013 BarA is a homologue of the yeast Lag1 acyl-CoA-dependent ceramide synthase, which catalyzes the condensation of phytosphingosine with a fatty acyl-CoA to form phytoceramide. Acyl Coenzyme A 38-46 sphingosine N-acyltransferase LAG1 Saccharomyces cerevisiae S288C 33-37 11694577-5 2001 The sphingolipid synthesis defect in lag1 Delta lac1 Delta cells can be partially corrected by overexpression of YPC1 or YDC1, encoding ceramidases that have been reported to have acyl-CoA-independent ceramide synthesis activity. Acyl Coenzyme A 180-188 sphingosine N-acyltransferase LAG1 Saccharomyces cerevisiae S288C 37-41 12105227-1 2002 The longevity assurance gene (LAG1) and its homolog (LAC1) are required for acyl-CoA-dependent synthesis of ceramides containing very long acyl chain (e.g. C26) fatty acids in yeast, and a homolog of LAG1, ASC1, confers resistance in plants to fumonisin B(1), an inhibitor of ceramide synthesis. Acyl Coenzyme A 76-84 sphingosine N-acyltransferase LAG1 Saccharomyces cerevisiae S288C 200-204