PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12912983-0 2003 Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. Acyl Coenzyme A 134-142 ceramide synthase 1 Homo sapiens 40-44 12105227-1 2002 The longevity assurance gene (LAG1) and its homolog (LAC1) are required for acyl-CoA-dependent synthesis of ceramides containing very long acyl chain (e.g. C26) fatty acids in yeast, and a homolog of LAG1, ASC1, confers resistance in plants to fumonisin B(1), an inhibitor of ceramide synthesis. Acyl Coenzyme A 76-84 ceramide synthase 1 Homo sapiens 30-34