PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14719590-3 2003 Earlier, I proposed that this could be due to low activities of delta6 and delta5 desaturases and consequent decreased plasma and tissue concentrations of long-chain polyunsaturated fatty acids of omega-6 and omega-3 series since perinatal period. long-chain polyunsaturated fatty acids 155-193 fatty acid desaturase 2 Homo sapiens 64-93 33530084-7 2021 In addition, genetic variants in FADS1, FADS2, ELOV-2, and ELOV-5 lead to a more efficient biosynthesis of long-chain polyunsaturated fatty acids (PUFAs), e.g., of linoleic acid (LA) to arachidonic acid (ARA), and (alpha-linolenic acid) (ALA) to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), leading to higher ARA levels. long-chain polyunsaturated fatty acids 107-145 fatty acid desaturase 2 Homo sapiens 40-45 29779171-1 2019 PURPOSE: Delta-5-desaturase (fatty acid desaturase-1, FADS1) and delta-6 desaturase (fatty acid desaturase-2, FADS2), rate-limiting enzymes in the biosynthesis of long-chain polyunsaturated fatty acids, may be associated with the risk of metabolic syndrome (MetS). long-chain polyunsaturated fatty acids 163-201 fatty acid desaturase 2 Homo sapiens 65-83 29779171-1 2019 PURPOSE: Delta-5-desaturase (fatty acid desaturase-1, FADS1) and delta-6 desaturase (fatty acid desaturase-2, FADS2), rate-limiting enzymes in the biosynthesis of long-chain polyunsaturated fatty acids, may be associated with the risk of metabolic syndrome (MetS). long-chain polyunsaturated fatty acids 163-201 fatty acid desaturase 2 Homo sapiens 85-108 29779171-1 2019 PURPOSE: Delta-5-desaturase (fatty acid desaturase-1, FADS1) and delta-6 desaturase (fatty acid desaturase-2, FADS2), rate-limiting enzymes in the biosynthesis of long-chain polyunsaturated fatty acids, may be associated with the risk of metabolic syndrome (MetS). long-chain polyunsaturated fatty acids 163-201 fatty acid desaturase 2 Homo sapiens 110-115 27932482-1 2017 The FADS1 and FADS2 genes in the FADS cluster encode the rate-limiting enzymes in the synthesis of long-chain polyunsaturated fatty acids (LC-PUFAs). long-chain polyunsaturated fatty acids 99-137 fatty acid desaturase 2 Homo sapiens 14-19 27311901-10 2016 DISCUSSION: Improving current understanding of FADS2-breastfeeding interaction may provide important biological insights regarding the importance of long-chain polyunsaturated fatty acids for the breastfeeding-IQ association. long-chain polyunsaturated fatty acids 149-187 fatty acid desaturase 2 Homo sapiens 47-52 25549244-7 2014 Based on these data, we suspected that the complete discontinuation of normal biosynthesis of long-chain polyunsaturated fatty acids (LC-PUFA) in HeLa was due to loss of FADS2 function. long-chain polyunsaturated fatty acids 94-132 fatty acid desaturase 2 Homo sapiens 170-175 34543890-1 2021 BACKGROUND: Variability in the FADS2 gene, which codifies the Delta-6 Desaturases and modulates the conversion of essential n-3 and n-6 fatty acids into long-chain polyunsaturated fatty acids, might modify the impact of prenatal supplementation with n-3 docosahexaenoic acid (DHA) on neurodevelopment. long-chain polyunsaturated fatty acids 153-191 fatty acid desaturase 2 Homo sapiens 31-36 33387849-1 2021 Long-chain polyunsaturated fatty acids (LCPUFAs) required for infant development are produced by Delta6 desaturase (D6D) and Delta5 desaturase (D5D). long-chain polyunsaturated fatty acids 0-38 fatty acid desaturase 2 Homo sapiens 103-114 33387849-1 2021 Long-chain polyunsaturated fatty acids (LCPUFAs) required for infant development are produced by Delta6 desaturase (D6D) and Delta5 desaturase (D5D). long-chain polyunsaturated fatty acids 0-38 fatty acid desaturase 2 Homo sapiens 116-119 32145021-1 2020 The FADS locus contains the genes FADS1 and FADS2 that encode enzymes involved in the synthesis of long-chain polyunsaturated fatty acids (LC-PUFA). long-chain polyunsaturated fatty acids 99-137 fatty acid desaturase 2 Homo sapiens 44-49 26513616-1 2016 Fatty acid desaturase genes (FADS1-FADS2) encode desaturases participating in the biosynthesis of long-chain polyunsaturated fatty acids. long-chain polyunsaturated fatty acids 98-136 fatty acid desaturase 2 Homo sapiens 35-40 20558833-3 2010 Delta-5 and delta-6 desaturases, FADS1 and FADS2, respectively, influence the serum, plasma and membrane phospholipid levels of LA, ALA and long-chain polyunsaturated fatty acids during pregnancy, lactation, and may influence an infant"s IQ, atopy and coronary heart disease (CHD) risk. long-chain polyunsaturated fatty acids 140-178 fatty acid desaturase 2 Homo sapiens 43-48