PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16052481-7	2005	The apoptotic dose of garcinol (20 microM) changed the ratio of the anti-apoptotic Bcl-2 and proapoptotic BAX proteins within 12 h, which correlated with a release of cytochrome c from the mitochondria to the cytosol, and with PARP cleavage.	garcinol	22-30	cytochrome c, somatic	Homo sapiens	167-179	
11312881-7	2001	Treatment with garcinol (20 microM) caused a rapid loss of mitochondrial transmembrane potential, release of mitochondrial cytochrome c into cytosol, and subsequent induction of procaspase-9 processing.	garcinol	15-23	cytochrome c, somatic	Homo sapiens	123-135	
11312881-12	2001	It is suggested that garcinol-induced apoptosis is triggered by the release of cytochrome c into the cytosol, procaspase-9 processing, activation of caspase-3 and caspase-2, degradation of PARP, and DNA fragmentation caused by the caspase-activated deoxyribonuclease through the digestion of DFF-45.	garcinol	21-29	cytochrome c, somatic	Homo sapiens	79-91	
11312881-0	2001	Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells.	garcinol	26-34	cytochrome c, somatic	Homo sapiens	56-68