PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7623781-1	1995	The effect of triiodothyronine (T3) on regulation of fatty acid synthase in chicken liver was investigated.	Triiodothyronine	14-30	fatty acid synthase	Gallus gallus	53-72	
9530133-3	1998	In the presence of triiodothyronine, glucose (25 mM) stimulated an increase in the activity and mRNA abundance of FAS and ME.	Triiodothyronine	19-35	fatty acid synthase	Gallus gallus	114-117	
7623781-1	1995	The effect of triiodothyronine (T3) on regulation of fatty acid synthase in chicken liver was investigated.	Triiodothyronine	32-34	fatty acid synthase	Gallus gallus	53-72	
1634532-1	1992	Hexanoate and octanoate inhibit the triiodothyronine (T3)-induced increases in the activities of malic enzyme and fatty acid synthase in chick embryo hepatocytes in culture.	Triiodothyronine	36-52	fatty acid synthase	Gallus gallus	114-133	
1634532-1	1992	Hexanoate and octanoate inhibit the triiodothyronine (T3)-induced increases in the activities of malic enzyme and fatty acid synthase in chick embryo hepatocytes in culture.	Triiodothyronine	54-56	fatty acid synthase	Gallus gallus	114-133	
1680129-0	1991	Triiodothyronine-induced accumulations of malic enzyme, fatty acid synthase, acetyl-coenzyme A carboxylase, and their mRNAs are blocked by protein kinase inhibitors.	Triiodothyronine	0-16	fatty acid synthase	Gallus gallus	56-75	
1680129-2	1991	Addition of triiodothyronine (T3) to chick-embryo hepatocytes in culture causes increased accumulations of malic enzyme, fatty acid synthase, acetyl-CoA carboxylase and their mRNAs.	Triiodothyronine	12-28	fatty acid synthase	Gallus gallus	121-140	
1680129-2	1991	Addition of triiodothyronine (T3) to chick-embryo hepatocytes in culture causes increased accumulations of malic enzyme, fatty acid synthase, acetyl-CoA carboxylase and their mRNAs.	Triiodothyronine	30-32	fatty acid synthase	Gallus gallus	121-140	
2170411-0	1990	Triiodothyronine stimulates transcription of the fatty acid synthase gene in chick embryo hepatocytes in culture.	Triiodothyronine	0-16	fatty acid synthase	Gallus gallus	49-68	
2170411-6	1990	In chick embryo hepatocytes in culture, the stimulatory effect of feeding on fatty acid synthase activity is mimicked by adding triiodothyronine and insulin; the inhibitory effect of starvation is mimicked by adding glucagon or cyclic AMP.	Triiodothyronine	128-144	fatty acid synthase	Gallus gallus	77-96	
2170411-7	1990	We now show that triiodothyronine alone stimulates transcription of fatty acid synthase by 4- to 6-fold, about the same as the increase in fatty acid synthase mRNA.	Triiodothyronine	17-33	fatty acid synthase	Gallus gallus	68-87	
3541753-1	1986	The levels of malic enzyme and fatty acid synthase are increased by feeding and decreased by starvation in liver in vivo and are increased by triiodothyronine and decreased by glucagon in hepatocytes in culture.	Triiodothyronine	142-158	fatty acid synthase	Gallus gallus	31-50	
3541753-6	1986	In chick-embryo hepatocytes incubated in serum-free medium containing insulin, triiodothyronine causes a greater than 10-fold increase in levels of both malic enzyme and fatty acid synthase mRNAs.	Triiodothyronine	79-95	fatty acid synthase	Gallus gallus	170-189	
3541753-7	1986	Kinetic and inhibitor experiments suggest a protein intermediate in the increases of malic enzyme and fatty acid synthase mRNAs caused by triiodothyronine.	Triiodothyronine	138-154	fatty acid synthase	Gallus gallus	102-121	
7945243-0	1994	Zinc, vanadate and selenate inhibit the tri-iodothyronine-induced expression of fatty acid synthase and malic enzyme in chick-embryo hepatocytes in culture.	Triiodothyronine	40-57	fatty acid synthase	Gallus gallus	80-99	
1586154-0	1992	Regulation of the malic enzyme and fatty acid synthase genes in chick embryo hepatocytes in culture: corticosterone and carnitine regulate responsiveness to triiodothyronine.	Triiodothyronine	157-173	fatty acid synthase	Gallus gallus	35-54	
3533937-3	1986	Triiodothyronine or insulin caused about a 2.5-fold increase in the relative rate of synthesis of fatty acid synthase.	Triiodothyronine	0-16	fatty acid synthase	Gallus gallus	98-117	
3533937-9	1986	Thus, triiodothyronine regulates fatty acid synthase primarily by controlling the amount of its mRNA.	Triiodothyronine	6-22	fatty acid synthase	Gallus gallus	33-52	
3533937-13	1986	After the addition of triiodothyronine, fatty acid synthase mRNA accumulated with sigmoidal kinetics, approaching a new steady state about 48 h after the addition of hormone.	Triiodothyronine	22-38	fatty acid synthase	Gallus gallus	40-59	
3533937-15	1986	We suggest that the abundances of both fatty acid synthase and malic enzyme mRNAs are regulated by a common triiodothyronine-induced peptide intermediate which has a relatively long half-life.	Triiodothyronine	108-124	fatty acid synthase	Gallus gallus	39-58