PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29108796-3 2018 Withanone (WS-2), a compound isolated from root extract of Withania somnifera at doses administered orally/day to wistar rats for duration of 21 days showed significant improvement in the cognitive skill by inhibiting amyloid beta-42 and attenuated the elevated levels of pro-inflammatory cytokines like TNF alpha, IL-1 beta, IL-6, MCP-1, Nitric oxide, lipid peroxidation and both beta- and gamma- secretase enzymatic activity. withanone 0-9 tumor necrosis factor Rattus norvegicus 304-313