PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22781593-4 2013 Using murine BaF3 cells, stably transformed with six different FGFR1 fusion genes, as well as human KG1 cells expressing activated chimeric FGFR1 and five newly established murine SCLL cell lines, we show that ponatinib (<50 nM) can effectively inhibit phosphoactivation of the fusion kinases and their downstream effectors, such as PLCgamma, Stat5 and Src. ponatinib 210-219 Rous sarcoma oncogene Mus musculus 356-359