PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31444999-14 2019 Ponatinib treatment significantly increased plasma VEGF, soluble (s)VEGFR1, sVEGFR2, sTIE2, interferon gamma (IFNgamma), tumor necrosis factor alpha (TNF-alpha), interleukin (IL)-6, IL-8, and IL-10 and decreased sVEGFR2. ponatinib 0-9 interleukin 6 Homo sapiens 162-180 30572654-3 2018 We found that Ponatinib inhibits STAT3 activity driven by EGF/EGFR, IL-6/IL-6R and IL-11/IL-11R, three major ligand/receptor systems involved in CRC development and progression. ponatinib 14-23 interleukin 6 Homo sapiens 68-72