PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23839497-5 2013 Further experiments in primary human keratinocytes preincubated with 1.2 mM calcium indicated that 1,25D and 10 muM delphinidin upregulate all five LCE3 genes (LCE3A-E). delphinidin 116-127 latexin Homo sapiens 112-115 24387788-8 2014 Catalytic activities of CYP2C9, CYP2A6, CYP2B6, and CYP3A4 enzymes were inhibited by all anthocyanidins to different extents (e.g., delphinidin inhibits CYP3A4 by >90% at 100 muM with IC50 = 32 muM). delphinidin 132-143 latexin Homo sapiens 178-181 24387788-8 2014 Catalytic activities of CYP2C9, CYP2A6, CYP2B6, and CYP3A4 enzymes were inhibited by all anthocyanidins to different extents (e.g., delphinidin inhibits CYP3A4 by >90% at 100 muM with IC50 = 32 muM). delphinidin 132-143 latexin Homo sapiens 197-200 29081896-4 2017 Both delphinidin and gallic acid generated oxygen-centred radicals at high (100 muM) concentrations in vitro. delphinidin 5-16 latexin Homo sapiens 80-83 29081896-5 2017 In a cultured human umbilical vein endothelial cell model of oxidative stress, the antioxidant protective effects of both delphinidin and gallic acid displayed a hormesic profile; 100 muM concentrations of both were cytotoxic, but relatively low concentrations (100 nM-1 muM) protected the cells and were associated with increased intracellular glutathione. delphinidin 122-133 latexin Homo sapiens 184-187 29081896-5 2017 In a cultured human umbilical vein endothelial cell model of oxidative stress, the antioxidant protective effects of both delphinidin and gallic acid displayed a hormesic profile; 100 muM concentrations of both were cytotoxic, but relatively low concentrations (100 nM-1 muM) protected the cells and were associated with increased intracellular glutathione. delphinidin 122-133 latexin Homo sapiens 271-274 23839497-7 2013 However, 20 muM delphinidin was capable of upregulating a luciferase reporter gene in a VDRE-dependent manner in a transfected keratinocyte cell line (KERTr). delphinidin 16-27 latexin Homo sapiens 12-15 23419638-6 2013 Enzyme kinetic analyses using human liver microsomes revealed inhibition of CYP1A1 activity by delphinidin (IC50 78 muM) and pelargonidin (IC50 33 muM). delphinidin 95-106 latexin Homo sapiens 116-119