PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32209725-7 2020 Through analyses of hypertrophic cardiomyocyte growth, fibrosis and cardiac function, delphinidin was demonstrated to confer resistance to aging- and transverse aortic constriction (TAC)-induced cardiac hypertrophy in vivo and attenuate Ang II-induced cardiomyocyte hypertrophy in vitro by significantly suppressing hypertrophic growth and the deposition of fibrosis. delphinidin 86-97 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 237-243 32209725-8 2020 Mechanistically, delphinidin reduced ROS accumulation upon Ang II stimulation through the direct activation of AMP-activated protein kinase (AMPK) and subsequent inhibition of the activity of Rac1 and expression of p47phox. delphinidin 17-28 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 59-65