PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19139002-7	2008	Delphinidin strongly suppressed Raf1 and MEK1 kinase activities and subsequently attenuated TPA-induced phosphorylation of MEK, extracellular signal-regulated kinase (ERK), p90RSK, and MSK.	delphinidin	0-11	v-raf-leukemia viral oncogene 1	Mus musculus	32-36	
19139002-8	2008	Although delphinidin suppressed ERK and c-Jun NH(2)-terminal kinase activities, it was more effective at inhibiting Raf1 or MEK1 activities.	delphinidin	9-20	v-raf-leukemia viral oncogene 1	Mus musculus	116-120	
19139002-9	2008	Pull-down and competition assays revealed that delphinidin binds with Raf1 or MEK1 noncompetitively with ATP.	delphinidin	47-58	v-raf-leukemia viral oncogene 1	Mus musculus	70-74	
19139002-11	2008	Together, these findings suggested that the targeted inhibition of Raf1 and MEK activities and COX-2 expression by delphinidin contribute to the chemopreventive potential of fruits and vegetables.	delphinidin	115-126	v-raf-leukemia viral oncogene 1	Mus musculus	67-71