PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15740068-6 2005 Moreover, delphinidin-induced apoptotic cell death was accompanied by up-regulation of Bax and down-regulation of Bcl-2 protein. delphinidin 10-21 BCL2 apoptosis regulator Homo sapiens 114-119 19818742-7 2010 Finally, delphinidin can efficiently prevent the down-regulation of Bcl-2 protein and up-regulation of Bax protein. delphinidin 9-20 BCL2 apoptosis regulator Homo sapiens 68-73 18729103-5 2009 We found that treatment of cells with delphinidin (30-240 microM; 48 h) resulted in (i) decrease in cell viability (ii) induction of apoptosis, (iii) cleavage of PARP, (iv) activation of caspases-3, -8, and -9, (v) increase in Bax with a concomitant decrease in Bcl-2 protein, and (vi) G2/M phase cell cycle arrest. delphinidin 38-49 BCL2 apoptosis regulator Homo sapiens 262-267 18623129-8 2008 Treatment of AU-565 cells with delphinidin resulted in (i) induction of apoptosis, (ii) cleavage of PARP protein, (iii) activation of caspase-3 and (iv) downregulation of Bcl-2 with an increase in the expression of Bax. delphinidin 31-42 BCL2 apoptosis regulator Homo sapiens 171-176 15740068-8 2005 Our experiments provide evidence that delphinidin is an effective apoptosis inducer in HepG(2) cells through regulation of Bcl-2 family moleculars and activation of c-Jun N-terminal kinase cascade. delphinidin 38-49 BCL2 apoptosis regulator Homo sapiens 123-128