PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24842127-3	2014	The results demonstrate that Saq-NO, but not Saq, potently decreased interleukin (IL)-10, IL-6 and nitrite accumulation and increased the levels of IL-1beta and tumour necrosis factor (TNF) in supernatants of mouse and rat macrophage cultures in vitro.	Saquinavir	29-32	tumor necrosis factor	Mus musculus	161-183	
24842127-3	2014	The results demonstrate that Saq-NO, but not Saq, potently decreased interleukin (IL)-10, IL-6 and nitrite accumulation and increased the levels of IL-1beta and tumour necrosis factor (TNF) in supernatants of mouse and rat macrophage cultures in vitro.	Saquinavir	29-32	tumor necrosis factor	Mus musculus	185-188	
15865214-6	2005	RESULTS: Nelfinavir, ritonavir and saquinavir inhibited adipogenesis and up-regulated the expression of TNF-alpha and IL-6, but this effect was not seen with indinavir, zidovudine and stavudine.	Saquinavir	35-45	tumor necrosis factor	Mus musculus	104-113	
15865214-9	2005	CONCLUSIONS: Our data suggest that the PIs nelfinavir, ritonavir and saquinavir have potent effects in inhibiting adipocyte differentiation whilst up-regulating TNF-alpha and IL-6 mRNA levels and decreasing adiponectin levels.	Saquinavir	69-79	tumor necrosis factor	Mus musculus	161-170