PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16790532-7 2006 Furthermore, the accumulation of two P-gp substrates, digoxin and saquinavir (an HIV-1 protease inhibitor), was enhanced (1.5- to 1.8-fold) in HIV-1(96ZM651) gp120-treated astrocyte monolayers but was not altered by P-gp inhibitors [e.g., valspodar (PSC833) and elacridar (GF120918)], suggesting a loss of transport activity. Saquinavir 66-76 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 158-163 12009872-6 2002 This occurs only in the situation in which the incorporated MuLV-Env protein has been activated to fusion activity by HIV protease-mediated removal of the C-terminal R-peptide and is completely inhibited when the respective particles are generated in the presence of the HIV protease inhibitor, Saquinavir. Saquinavir 295-305 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 65-68