PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9099730-3 1997 We report herein that DL-threo-dihydrosphingosine (DHS), a competitive inhibitor of sphingosine kinase that prevents PDGF-induced SPP formation, specifically inhibited the activation of two cyclin-dependent kinases (p34(cdc2) kinase and Cdk2 kinase) induced by PDGF, but not by EGF. dhs 51-54 epidermal growth factor Homo sapiens 278-281