PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10336821-7 1999 In vitro treatment with hCG and protein kinase A (PKA) activators (dbcAMP and forskolin) induced ovarian Cx32.2 mRNA levels and OMC. Bucladesine 67-73 hypertrichosis 2 (generalised, congenital) Homo sapiens 24-27 8761965-7 1996 Exogenous dibutyryl cAMP increased hCG and progesterone release by normoxic trophoblast but not by hypoxic cells. Bucladesine 10-24 hypertrichosis 2 (generalised, congenital) Homo sapiens 35-38 9785042-6 1998 In contrast, db-cAMP inhibites hCG secretion into the medium. Bucladesine 13-20 hypertrichosis 2 (generalised, congenital) Homo sapiens 31-34 6279742-3 1981 2) When dbcAMP was added to chorionic villi, there was a significant increase estradiol production in chorionic villi and hCG secretion in media. Bucladesine 8-14 hypertrichosis 2 (generalised, congenital) Homo sapiens 122-125 6100037-3 1984 Steroidogenic desensitization to Bt2 cAMP and hCG stimulation in vitro was observed with both doses of hCG administered in vivo. Bucladesine 33-41 hypertrichosis 2 (generalised, congenital) Homo sapiens 103-106 6198267-7 1983 Other agents reported to influence hCG production by different types of cell cultures include dibutyryl cyclic AMP, epidermal growth factor (EGF), methotrexate, and hydroxyurea. Bucladesine 94-114 hypertrichosis 2 (generalised, congenital) Homo sapiens 35-38 6282920-8 1982 Basal progesterone, basal hCG, and dbcAMP-stimulated hCG outputs were unaffected by the addition of LDL or DHEAS. Bucladesine 35-41 hypertrichosis 2 (generalised, congenital) Homo sapiens 53-56 6279190-6 1982 Increasing duration (12--72 h) of treatment with insulin resulted in time-dependent increases in the hCG-stimulated accumulation of testosterone achieving statistical significance (P less than 0.05) by 36 h. In addition, pretreatment with insulin (10 micrograms/ml) brought about significant (P less than 0.01) increases in the choleragen and Bt2cAMP-stimulated accumulation of testosterone. Bucladesine 343-350 hypertrichosis 2 (generalised, congenital) Homo sapiens 101-104 6279742-5 1981 4) When dbcAMP or synthetic LH-RH was added to BeWo cells, increased secretion of hCG and estradiol into media was seen. Bucladesine 8-14 hypertrichosis 2 (generalised, congenital) Homo sapiens 82-85 15224149-6 2004 Further experiments showed that dbcAMP (100 micromol/L) obviously increased hCG-induced testosterone secretion and integral optical density (IOD) immunostaining of Myb in Leydig cells. Bucladesine 32-38 hypertrichosis 2 (generalised, congenital) Homo sapiens 76-79 21562093-5 2011 Activation of the cAMP pathway with dibutyryl cAMP (db cAMP) or forskolin recapitulated the stimulatory effect of hCG on leptin expression. Bucladesine 36-50 hypertrichosis 2 (generalised, congenital) Homo sapiens 114-117 17400803-4 2007 Using MA-10 mouse Leydig tumor cells, we demonstrate that the activation of PKC and PKA signaling, by phorbol-12-myristate-13-acetate (PMA) and dibutyryl cAMP (dbcAMP)/human chorionic gonadotropin (hCG) respectively, was able to phosphorylate ERK1/2, an event markedly decreased by an upstream kinase inhibitor, U0126. Bucladesine 160-166 hypertrichosis 2 (generalised, congenital) Homo sapiens 198-201 14636638-9 2003 The up-regulation of follistatin expression by hCG could be mimicked by all the drugs that increase the intracellular cAMP level including 8-Br-cAMP, db-cAMP, forskolin, and 3-isobutyl-1-methylxanthine (IBMX). Bucladesine 150-157 hypertrichosis 2 (generalised, congenital) Homo sapiens 47-50