PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15224149-6	2004	Further experiments showed that dbcAMP (100 micromol/L) obviously increased hCG-induced testosterone secretion and integral optical density (IOD) immunostaining of Myb in Leydig cells.	Bucladesine	32-38	hypertrichosis 2 (generalised, congenital)	Homo sapiens	76-79	
14636638-9	2003	The up-regulation of follistatin expression by hCG could be mimicked by all the drugs that increase the intracellular cAMP level including 8-Br-cAMP, db-cAMP, forskolin, and 3-isobutyl-1-methylxanthine (IBMX).	Bucladesine	150-157	hypertrichosis 2 (generalised, congenital)	Homo sapiens	47-50	
9785042-6	1998	In contrast, db-cAMP inhibites hCG secretion into the medium.	Bucladesine	13-20	hypertrichosis 2 (generalised, congenital)	Homo sapiens	31-34	
8761965-7	1996	Exogenous dibutyryl cAMP increased hCG and progesterone release by normoxic trophoblast but not by hypoxic cells.	Bucladesine	10-24	hypertrichosis 2 (generalised, congenital)	Homo sapiens	35-38	
6198267-7	1983	Other agents reported to influence hCG production by different types of cell cultures include dibutyryl cyclic AMP, epidermal growth factor (EGF), methotrexate, and hydroxyurea.	Bucladesine	94-114	hypertrichosis 2 (generalised, congenital)	Homo sapiens	35-38	
6279190-6	1982	Increasing duration (12--72 h) of treatment with insulin resulted in time-dependent increases in the hCG-stimulated accumulation of testosterone achieving statistical significance (P less than 0.05) by 36 h. In addition, pretreatment with insulin (10 micrograms/ml) brought about significant (P less than 0.01) increases in the choleragen and Bt2cAMP-stimulated accumulation of testosterone.	Bucladesine	343-350	hypertrichosis 2 (generalised, congenital)	Homo sapiens	101-104	
6279742-3	1981	2) When dbcAMP was added to chorionic villi, there was a significant increase estradiol production in chorionic villi and hCG secretion in media.	Bucladesine	8-14	hypertrichosis 2 (generalised, congenital)	Homo sapiens	122-125	
6279742-5	1981	4) When dbcAMP or synthetic LH-RH was added to BeWo cells, increased secretion of hCG and estradiol into media was seen.	Bucladesine	8-14	hypertrichosis 2 (generalised, congenital)	Homo sapiens	82-85	
17400803-4	2007	Using MA-10 mouse Leydig tumor cells, we demonstrate that the activation of PKC and PKA signaling, by phorbol-12-myristate-13-acetate (PMA) and dibutyryl cAMP (dbcAMP)/human chorionic gonadotropin (hCG) respectively, was able to phosphorylate ERK1/2, an event markedly decreased by an upstream kinase inhibitor, U0126.	Bucladesine	160-166	hypertrichosis 2 (generalised, congenital)	Homo sapiens	198-201	
10336821-7	1999	In vitro treatment with hCG and protein kinase A (PKA) activators (dbcAMP and forskolin) induced ovarian Cx32.2 mRNA levels and OMC.	Bucladesine	67-73	hypertrichosis 2 (generalised, congenital)	Homo sapiens	24-27	
6100037-3	1984	Steroidogenic desensitization to Bt2 cAMP and hCG stimulation in vitro was observed with both doses of hCG administered in vivo.	Bucladesine	33-41	hypertrichosis 2 (generalised, congenital)	Homo sapiens	103-106	
6282920-8	1982	Basal progesterone, basal hCG, and dbcAMP-stimulated hCG outputs were unaffected by the addition of LDL or DHEAS.	Bucladesine	35-41	hypertrichosis 2 (generalised, congenital)	Homo sapiens	53-56	
21562093-5	2011	Activation of the cAMP pathway with dibutyryl cAMP (db cAMP) or forskolin recapitulated the stimulatory effect of hCG on leptin expression.	Bucladesine	36-50	hypertrichosis 2 (generalised, congenital)	Homo sapiens	114-117