PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11193379-14 2000 Similarly, dbcAMP inhibited the production of IFN-gamma and IL-2 more potently than that of IL-4 and IL-5. Bucladesine 11-17 interleukin 2 Homo sapiens 60-64 11602691-2 2001 Addition of dibutyryl cAMP mimicked rolipram inhibitions on proliferation, IL-2, TNF-alpha, and IFN-gamma but not on IL-10 or IL-5 production. Bucladesine 12-26 interleukin 2 Homo sapiens 75-79 10102795-7 1999 IL-2 production was also inhibited by dbcAMP in the presence of HA1004 and Rp-cAMPS. Bucladesine 38-44 interleukin 2 Homo sapiens 0-4 9502171-8 1998 Similarly, dbcAMP inhibited the production of IFN-gamma and IL-2 more potently than IL-4 and IL-5. Bucladesine 11-17 interleukin 2 Homo sapiens 60-64 8858999-5 1996 cAMP-elevating agents, such as PGE2, forskolin and dibutyryl cAMP, suppressed IL-2, IL-4 and IL-5 production by concanavalin A-stimulated PBMC in a manner similar to that of T-440. Bucladesine 51-65 interleukin 2 Homo sapiens 78-82 2175326-10 1990 In addition, we also demonstrate that NK cell cytotoxic activation induced by IL-2 is still demonstrable in the presence of Bt2cAMP under conditions in which NK cell proliferation is blocked. Bucladesine 124-131 interleukin 2 Homo sapiens 78-82 1333364-3 1992 The augmentative effect of dbcAMP in PBMC cultures was due to an increase in IL-2 production and not to increased in IL-2R-alpha chain expression. Bucladesine 27-33 interleukin 2 Homo sapiens 77-81 1333364-9 1992 Taken together, our results indicate that cAMP can play a positive regulatory role in T cell proliferation due to factor(s) secreted by dbcAMP-treated monocytes resulting in increased IL-2 synthesis in T cells. Bucladesine 136-142 interleukin 2 Homo sapiens 184-188 2473111-3 1989 Preincubation with dibutyryl-cAMP restored the ability of the truncated Ia expressing-transfectant to stimulate IL-2 release by otherwise nonresponsive T hybrids. Bucladesine 19-33 interleukin 2 Homo sapiens 112-116 6257625-5 1980 In addition, both L-isoproterenol and DBcAMP in the presence of theophylline decreased LK-induced macrophage aggregation, whereas D-isoproterenol and DBcGMP had no effect. Bucladesine 38-44 interleukin 2 Homo sapiens 87-89 2842097-2 1988 Dibutyryl cyclic AMP markedly suppressed NK, IL-2-augmented NK and ADCC activities in a dose-dependent manner but not previously induced LAK activity. Bucladesine 0-20 interleukin 2 Homo sapiens 45-49 6096309-2 1984 The addition of either N6,O2-dibutyryl cyclic AMP (DB-cAMP), aminophylline or isoproterenol to CTC cultures significantly suppressed the proliferation of CTC stimulated by either PHA or IL-2. Bucladesine 23-49 interleukin 2 Homo sapiens 186-190 6096309-2 1984 The addition of either N6,O2-dibutyryl cyclic AMP (DB-cAMP), aminophylline or isoproterenol to CTC cultures significantly suppressed the proliferation of CTC stimulated by either PHA or IL-2. Bucladesine 51-58 interleukin 2 Homo sapiens 186-190