PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11178987-1	2001	Aminoglutethimide (AMG), a potent inhibitor of steroidogenesis used in the treatment of breast cancer and some adrenal pathologies, abolished the induction of ornithine decarboxylase (ODC) elicited by peptide hormones and by dibutyryl-cAMP in steroidogenic tissues.	Bucladesine	225-239	ornithine decarboxylase 1	Homo sapiens	159-182	
11178987-1	2001	Aminoglutethimide (AMG), a potent inhibitor of steroidogenesis used in the treatment of breast cancer and some adrenal pathologies, abolished the induction of ornithine decarboxylase (ODC) elicited by peptide hormones and by dibutyryl-cAMP in steroidogenic tissues.	Bucladesine	225-239	ornithine decarboxylase 1	Homo sapiens	184-187	
2478272-2	1989	Induction of differentiation with either retinoic acid, dimethylsulfoxide, dibutyryl cAMP or dihydroxy-vitamin D3 resulted in a decrease of the cellular content of ODC RNA.	Bucladesine	75-89	ornithine decarboxylase 1	Homo sapiens	164-167	
1652247-3	1991	RNA blot assays indicate that butyrate and dbcAMP decrease the expression of ornithine decarboxylase and c-myc genes, and stimulate the expression of the vimentin gene.	Bucladesine	43-49	ornithine decarboxylase 1	Homo sapiens	77-100	
6180738-2	1982	Addition of dibutyryl cyclic AMP or 3-isobutyl-1-methylxanthine at the time of serum re-feeding further stimulated ODC activity in 3T3 fibroblasts but inhibited the serum stimulation of ODC activity in FS fibroblasts.	Bucladesine	12-32	ornithine decarboxylase 1	Homo sapiens	115-118	
2578206-6	1985	Addition of isoproterenol (10(-7)M), IBMX (1 mM) or dibutyryl cAMP (2.5 mM) to isolated aortic segments cultured in minimal salts-glucose media evoked decreases in basal levels of ODC activity resembling those observed in the intact animal.	Bucladesine	52-66	ornithine decarboxylase 1	Homo sapiens	180-183	
6180738-2	1982	Addition of dibutyryl cyclic AMP or 3-isobutyl-1-methylxanthine at the time of serum re-feeding further stimulated ODC activity in 3T3 fibroblasts but inhibited the serum stimulation of ODC activity in FS fibroblasts.	Bucladesine	12-32	ornithine decarboxylase 1	Homo sapiens	186-189	
6249374-2	1980	Each of these amino acids induced a striking activation of ornithine decarboxylase in the presence of dibutyryl cyclic AMP and luteinizing hormone.	Bucladesine	102-122	ornithine decarboxylase 1	Homo sapiens	59-82	
6249374-4	1980	The active amino acids at optimal concentrations (10 mM) induced only a 10-20 fold enhancement of enzyme activity alone, while in the presence of dibutyryl cyclic AMP, ornithine decarboxylase activity was increased 40-50 fold within 7-8 h. Of the hormones and drugs tested, luteinizing hormone resulted in the highest (300-500 fold) induction of ornithine decarboxylase with optimal concentrations of dibutyryl cyclic AMP and asparagnine.	Bucladesine	146-166	ornithine decarboxylase 1	Homo sapiens	168-191	
6249374-4	1980	The active amino acids at optimal concentrations (10 mM) induced only a 10-20 fold enhancement of enzyme activity alone, while in the presence of dibutyryl cyclic AMP, ornithine decarboxylase activity was increased 40-50 fold within 7-8 h. Of the hormones and drugs tested, luteinizing hormone resulted in the highest (300-500 fold) induction of ornithine decarboxylase with optimal concentrations of dibutyryl cyclic AMP and asparagnine.	Bucladesine	146-166	ornithine decarboxylase 1	Homo sapiens	346-369	
6249374-6	1980	The induction of ornithine decarboxylase elicited by dibutyryl cyclic AMP, amino acid and luteinizing hormone was diminished about 50% with inhibitors of RNA and protein synthesis.	Bucladesine	53-73	ornithine decarboxylase 1	Homo sapiens	17-40	
6249374-10	1980	The induction of ornithine decarboxylase by dibutyryl cyclic AMP and luteinizing hormone was additive in the presence of an active amino acid.	Bucladesine	44-64	ornithine decarboxylase 1	Homo sapiens	17-40	
85547-4	1978	N,O"-Dibutyryl cAMP (1.0--10.0 mM) caused a dose-dependent stimulation of ODC activity which equaled the maximal effect of LH but was significantly less effective than the saturating dose of FSH.	Bucladesine	0-19	ornithine decarboxylase 1	Homo sapiens	74-77	
166887-0	1975	Involvement of hypophysis in the stimulation of liver ornithine decarboxylase by dibutyryl cyclic AMP.	Bucladesine	81-101	ornithine decarboxylase 1	Homo sapiens	54-77