PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21186580-4	2006	The changes both of protein and gene expression of heme oxygenase-1 in rats" myocardium, which were induced by injection of LPS or preadministration of the specific inhibitor of NF-kappaB, pyrrolidine dithiocarbamate(PDTC), were examined by immunochemistry of reverse transcripted polymerase chain reaction.	pyrrolidine dithiocarbamic acid	189-216	heme oxygenase 1	Rattus norvegicus	51-67	
17098045-1	2006	PURPOSE: We investigated whether pharmacologically induced up-regulation of heme oxygenase 1 by pyrrolidine dithiocarbamate (PDTC) conferred protection against subsequent ischemia-reperfusion injury (IRI) to the rat liver after temporary vascular occlusion of 70% of the organ.	pyrrolidine dithiocarbamic acid	96-123	heme oxygenase 1	Rattus norvegicus	76-92	
17098045-1	2006	PURPOSE: We investigated whether pharmacologically induced up-regulation of heme oxygenase 1 by pyrrolidine dithiocarbamate (PDTC) conferred protection against subsequent ischemia-reperfusion injury (IRI) to the rat liver after temporary vascular occlusion of 70% of the organ.	pyrrolidine dithiocarbamic acid	125-129	heme oxygenase 1	Rattus norvegicus	76-92	
9837857-0	1998	Transcriptional regulation of the heme oxygenase 1 gene by pyrrolidine dithiocarbamate.	pyrrolidine dithiocarbamic acid	59-86	heme oxygenase 1	Rattus norvegicus	34-50	
14697299-0	2003	Induction of heme oxygenase-1 and dilatation of hepatic sinusoids by an administration of pyrrolidine dithiocarbamate in rat livers.	pyrrolidine dithiocarbamic acid	90-117	heme oxygenase 1	Rattus norvegicus	13-29	
14697299-2	2003	In this article, we report our use of pyrrolidine dithiocarbamate (PDTC) to induce HO-1 in the liver in vivo and its impact on hepatic microcirculation.	pyrrolidine dithiocarbamic acid	38-65	heme oxygenase 1	Rattus norvegicus	83-87	
14697299-2	2003	In this article, we report our use of pyrrolidine dithiocarbamate (PDTC) to induce HO-1 in the liver in vivo and its impact on hepatic microcirculation.	pyrrolidine dithiocarbamic acid	67-71	heme oxygenase 1	Rattus norvegicus	83-87	
12773984-0	2003	Pyrrolidine dithiocarbamate provides protection against hypothermic preservation and transplantation injury in the rat liver: the role of heme oxygenase-1.	pyrrolidine dithiocarbamic acid	0-27	heme oxygenase 1	Rattus norvegicus	138-154	
12773984-1	2003	BACKGROUND: Pyrrolidine dithiocarbamate (PDTC) represents a class of antioxidants and is a potent inducer of the heme oxygenase-1 (HO-1) gene and an inhibitor of nuclear factor-kappa B (NF-kappa B).	pyrrolidine dithiocarbamic acid	12-39	heme oxygenase 1	Rattus norvegicus	113-129	
12773984-1	2003	BACKGROUND: Pyrrolidine dithiocarbamate (PDTC) represents a class of antioxidants and is a potent inducer of the heme oxygenase-1 (HO-1) gene and an inhibitor of nuclear factor-kappa B (NF-kappa B).	pyrrolidine dithiocarbamic acid	12-39	heme oxygenase 1	Rattus norvegicus	131-135	
12773984-1	2003	BACKGROUND: Pyrrolidine dithiocarbamate (PDTC) represents a class of antioxidants and is a potent inducer of the heme oxygenase-1 (HO-1) gene and an inhibitor of nuclear factor-kappa B (NF-kappa B).	pyrrolidine dithiocarbamic acid	41-45	heme oxygenase 1	Rattus norvegicus	113-129	
12773984-1	2003	BACKGROUND: Pyrrolidine dithiocarbamate (PDTC) represents a class of antioxidants and is a potent inducer of the heme oxygenase-1 (HO-1) gene and an inhibitor of nuclear factor-kappa B (NF-kappa B).	pyrrolidine dithiocarbamic acid	41-45	heme oxygenase 1	Rattus norvegicus	131-135	
9837857-2	1998	We recently characterized the induction of HO-1 gene expression by nitric oxide (NO) and postulated that the addition of an antioxidant, such as pyrrolidine dithiocarbamate (PDTC), would attenuate HO-1 induction in response to NO.	pyrrolidine dithiocarbamic acid	174-178	heme oxygenase 1	Rattus norvegicus	197-201	
9837857-2	1998	We recently characterized the induction of HO-1 gene expression by nitric oxide (NO) and postulated that the addition of an antioxidant, such as pyrrolidine dithiocarbamate (PDTC), would attenuate HO-1 induction in response to NO.	pyrrolidine dithiocarbamic acid	145-172	heme oxygenase 1	Rattus norvegicus	43-47	
9837857-2	1998	We recently characterized the induction of HO-1 gene expression by nitric oxide (NO) and postulated that the addition of an antioxidant, such as pyrrolidine dithiocarbamate (PDTC), would attenuate HO-1 induction in response to NO.	pyrrolidine dithiocarbamic acid	145-172	heme oxygenase 1	Rattus norvegicus	197-201	
9837857-2	1998	We recently characterized the induction of HO-1 gene expression by nitric oxide (NO) and postulated that the addition of an antioxidant, such as pyrrolidine dithiocarbamate (PDTC), would attenuate HO-1 induction in response to NO.	pyrrolidine dithiocarbamic acid	174-178	heme oxygenase 1	Rattus norvegicus	43-47	
29161661-7	2018	The NF-kB inhibitor pyrrolidine dithiocarbamate (PDTC) increased Nrf2 nuclear translocation and HO-1 expression and antioxidant levels.	pyrrolidine dithiocarbamic acid	20-47	heme oxygenase 1	Rattus norvegicus	96-100	
29161661-7	2018	The NF-kB inhibitor pyrrolidine dithiocarbamate (PDTC) increased Nrf2 nuclear translocation and HO-1 expression and antioxidant levels.	pyrrolidine dithiocarbamic acid	49-53	heme oxygenase 1	Rattus norvegicus	96-100	
22064360-6	2012	DTF suppressed NF-kappaB activation, and addition of NF-kappaB inhibitor, pyrrolidine dithiocarbamate or Bay 11-7082, synergistically enhanced DTF-mediated HO-1 expression, indicating that HO-1 induction is associated with NF-kappaB suppression.	pyrrolidine dithiocarbamic acid	74-101	heme oxygenase 1	Rattus norvegicus	156-160	
22064360-6	2012	DTF suppressed NF-kappaB activation, and addition of NF-kappaB inhibitor, pyrrolidine dithiocarbamate or Bay 11-7082, synergistically enhanced DTF-mediated HO-1 expression, indicating that HO-1 induction is associated with NF-kappaB suppression.	pyrrolidine dithiocarbamic acid	74-101	heme oxygenase 1	Rattus norvegicus	189-193