PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11811521-10 2001 In PBMCs and Jurkat T cells (subclones JR and JE6.1), this activation could be inhibited by pre-treatment with the antioxidants, pyrrolidine dithiocarbamate (PDTC) and N-acetyl-L-cysteine (NAC). pyrrolidine dithiocarbamic acid 129-156 X-linked Kx blood group Homo sapiens 189-192 16490171-1 2006 AIM: To study the effects of N-acetyl-L-cysteine (NAC) and pyrrolidine dithiocarbamate (PDTC) on the phosphorylation of IkappaB kinase (IKK) beta, IKK alpha, and IkB alpha in alveolar macrophages (AM), and to explore the pharmacological mechanisms of NAC and PDTC as inhibitors of NF-kappaB activation. pyrrolidine dithiocarbamic acid 59-86 X-linked Kx blood group Homo sapiens 251-254 16490171-1 2006 AIM: To study the effects of N-acetyl-L-cysteine (NAC) and pyrrolidine dithiocarbamate (PDTC) on the phosphorylation of IkappaB kinase (IKK) beta, IKK alpha, and IkB alpha in alveolar macrophages (AM), and to explore the pharmacological mechanisms of NAC and PDTC as inhibitors of NF-kappaB activation. pyrrolidine dithiocarbamic acid 88-92 X-linked Kx blood group Homo sapiens 251-254 12163056-5 2002 Pyrrolidine dithiocarbamate (PDTC) also suppressed the level of expression CD11a/LFA-1alpha protein, although the effect of PDTC was less potent than NAC. pyrrolidine dithiocarbamic acid 0-27 X-linked Kx blood group Homo sapiens 150-153 12163056-5 2002 Pyrrolidine dithiocarbamate (PDTC) also suppressed the level of expression CD11a/LFA-1alpha protein, although the effect of PDTC was less potent than NAC. pyrrolidine dithiocarbamic acid 29-33 X-linked Kx blood group Homo sapiens 150-153 15532722-4 2004 Western blot evaluation revealed SEA was able to induce nuclear translocation of NF-kappaB from cytosol to nucleus in PBMC, which could be abolished by a NF-kappaB inhibitor such as pyrrolidine dithiocarbamate (PDTC), sodium pyrithione (Pyri), N-acetyl-L-cysteine (NAC), or curcumin (Cur). pyrrolidine dithiocarbamic acid 182-209 X-linked Kx blood group Homo sapiens 265-268 15532722-4 2004 Western blot evaluation revealed SEA was able to induce nuclear translocation of NF-kappaB from cytosol to nucleus in PBMC, which could be abolished by a NF-kappaB inhibitor such as pyrrolidine dithiocarbamate (PDTC), sodium pyrithione (Pyri), N-acetyl-L-cysteine (NAC), or curcumin (Cur). pyrrolidine dithiocarbamic acid 211-215 X-linked Kx blood group Homo sapiens 265-268 11811521-10 2001 In PBMCs and Jurkat T cells (subclones JR and JE6.1), this activation could be inhibited by pre-treatment with the antioxidants, pyrrolidine dithiocarbamate (PDTC) and N-acetyl-L-cysteine (NAC). pyrrolidine dithiocarbamic acid 158-162 X-linked Kx blood group Homo sapiens 189-192 31999475-6 2020 The NF-kappaB inhibitor, pyrrolidine dithiocarbamate (PDTC), alleviated UVB-induced apoptosis in HLECs; while activation of NF-kappaB suppressed the effects of the ROS inhibitor, N-acetyl-L-cysteine (NAC), on UVB-treated HLECs. pyrrolidine dithiocarbamic acid 25-52 X-linked Kx blood group Homo sapiens 200-203 11181056-6 2001 In addition, PDTC-induced activation of HSF1 was significantly inhibited by NAC and a thiol-reducing agent dithiothreitol (DTT), while it was partially prevented by other antioxidants, AA, BHT, and PG. pyrrolidine dithiocarbamic acid 13-17 X-linked Kx blood group Homo sapiens 76-79 31999475-6 2020 The NF-kappaB inhibitor, pyrrolidine dithiocarbamate (PDTC), alleviated UVB-induced apoptosis in HLECs; while activation of NF-kappaB suppressed the effects of the ROS inhibitor, N-acetyl-L-cysteine (NAC), on UVB-treated HLECs. pyrrolidine dithiocarbamic acid 54-58 X-linked Kx blood group Homo sapiens 200-203 25871324-9 2015 The effects of 5"-Cl on mitochondria and apoptosis were substantially blocked in the presence of a combination between z-VAD-FMK and either of the ROS scavenger N-acetyl-L-cysteine (NAC) or pyrrolidine dithiocarbamate (PDTC). pyrrolidine dithiocarbamic acid 190-217 X-linked Kx blood group Homo sapiens 182-185 25871324-9 2015 The effects of 5"-Cl on mitochondria and apoptosis were substantially blocked in the presence of a combination between z-VAD-FMK and either of the ROS scavenger N-acetyl-L-cysteine (NAC) or pyrrolidine dithiocarbamate (PDTC). pyrrolidine dithiocarbamic acid 219-223 X-linked Kx blood group Homo sapiens 182-185 28184939-11 2017 Nevertheless, IL-17A-induced expression of MMP-2/9 and OE19 cell invasiveness were both inhibited by pretreatment with N-acetyl-L-cysteine (NAC, a ROS scavenger) or pyrrolidine dithiocarbamate (PDTC, a NF-kappaB inhibitor). pyrrolidine dithiocarbamic acid 165-192 X-linked Kx blood group Homo sapiens 140-143 28184939-11 2017 Nevertheless, IL-17A-induced expression of MMP-2/9 and OE19 cell invasiveness were both inhibited by pretreatment with N-acetyl-L-cysteine (NAC, a ROS scavenger) or pyrrolidine dithiocarbamate (PDTC, a NF-kappaB inhibitor). pyrrolidine dithiocarbamic acid 194-198 X-linked Kx blood group Homo sapiens 140-143