PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28484848-6	2017	Further study indicated that the presence of either NF-kappaB inhibitor pyrrolidinedithiocarbamate or prior silencing miR-27a/b with anti-miRNA oligonucleotides suppressed ET-1-induced PPARgamma reduction and proliferation of PASMC, while overexpression of miR-27a/b reduced PPARgamma expression and enhanced PASMC proliferation.	pyrrolidine dithiocarbamic acid	72-98	endothelin 1	Rattus norvegicus	172-176	
23619396-5	2013	The effect of ET-1 was diminished by an ETB antagonist (1 muM BQ788) or inhibitors of Sp1 (500 nM mithramycin), ERK (50 muM PD98059), p38 (20 muM SB203580) and JNK (1 muM SP600125), but not inhibitors of NF-kappaB (10 muM SN50 and 100 muM pyrrolidine dithiocarbamate).	pyrrolidine dithiocarbamic acid	239-266	endothelin 1	Rattus norvegicus	14-18	
23627909-13	2013	The increase in CCL2 and CXCL1 expression by ET-1 was inhibited by actinomycin D, pyrrolidine dithiocarbamate, SN50, mithramycin, SB203580 and SP600125.	pyrrolidine dithiocarbamic acid	82-109	endothelin 1	Rattus norvegicus	45-49	
19748488-5	2009	In addition, ET-1 was able to elicit reactive oxygen species (ROS) generation and mitogen-activated protein kinase (MAPK) activation, and antioxidant pyrrolidine dithiocarbamate and p38MAPK inhibitor SB203580 inhibited ET-1-induced CRP expression.	pyrrolidine dithiocarbamic acid	150-177	endothelin 1	Rattus norvegicus	219-223	
22569294-7	2012	In addition, pyrrolidine-dithiocarbamate completely suppressed not only NF-kappaB activation but also renal dysfunction and ET-1 overproduction.	pyrrolidine dithiocarbamic acid	13-40	endothelin 1	Rattus norvegicus	124-128	
18722366-8	2008	Ischemia and reperfusion significantly increased the mRNA expression of the endothelin-1 and endothelin ET(B) receptor, which was prevented by pyrrolidine dithiocarbamate.	pyrrolidine dithiocarbamic acid	143-170	endothelin 1	Rattus norvegicus	76-88