PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15155187-9 2004 Activation of ERK1/2 and the 46-kDa p-JNK protein was enhanced by LPS and LPS-PMA and was significantly inhibited by MXF (54 and 42%, respectively, with MXF at 10 microg/ml). Moxifloxacin 117-120 mitogen-activated protein kinase 8 Homo sapiens 38-41 17012372-0 2007 Moxifloxacin but not ciprofloxacin or azithromycin selectively inhibits IL-8, IL-6, ERK1/2, JNK, and NF-kappaB activation in a cystic fibrosis epithelial cell line. Moxifloxacin 0-12 mitogen-activated protein kinase 8 Homo sapiens 92-95 15155187-9 2004 Activation of ERK1/2 and the 46-kDa p-JNK protein was enhanced by LPS and LPS-PMA and was significantly inhibited by MXF (54 and 42%, respectively, with MXF at 10 microg/ml). Moxifloxacin 153-156 mitogen-activated protein kinase 8 Homo sapiens 38-41 15155187-10 2004 We conclude that MXF suppresses the secretion of proinflammatory cytokines in human monocytes and THP-1 cells and that it exerts its anti-inflammatory effects in THP-1 cells by inhibiting NF-kappaB, ERK, and JNK activation. Moxifloxacin 17-20 mitogen-activated protein kinase 8 Homo sapiens 208-211