PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31230886-0 2019 Corrigendum to "CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance" [Eur. Quinazolinones 188-202 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 144-150 31230886-0 2019 Corrigendum to "CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance" [Eur. Quinazolinones 188-202 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 206-212 30776468-0 2019 CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance. Quinazolinones 172-186 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 128-134 30776468-0 2019 CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance. Quinazolinones 172-186 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 190-196 30776468-4 2019 With live cell-based assays, quinazolinones 9i/9b were found to be selective CYP1A1/CYP1B1 inhibitors with IC50 values of 30/21 nM, and > 150-fold selectivity over CYP2/3 enzymes, whereas they were far less active using commercially-available CYP1A1/CYP1B1 microsomal enzymes (IC50, >10/1.3-1.7 muM). Quinazolinones 29-43 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 77-83 30776468-4 2019 With live cell-based assays, quinazolinones 9i/9b were found to be selective CYP1A1/CYP1B1 inhibitors with IC50 values of 30/21 nM, and > 150-fold selectivity over CYP2/3 enzymes, whereas they were far less active using commercially-available CYP1A1/CYP1B1 microsomal enzymes (IC50, >10/1.3-1.7 muM). Quinazolinones 29-43 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 246-252