PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24286396-2	2014	The ability of these compounds to inhibit cyclooxygenase (COX-1 and 2) enzyme has been determined in-vitro; the results indicated that quinazolinone derivatives were selective towards COX-2 rather than COX-1.	Quinazolinones	135-148	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	184-189	
24286396-3	2014	Among the quinazolinone derivatives tested, compound 32 showed better inhibition against COX-2 when compared with Celecoxib.	Quinazolinones	10-23	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	89-94	
34338135-0	2021	Design and synthesis of novel quinazolinones conjugated ibuprofen, indole acetamide, or thioacetohydrazide as selective COX-2 inhibitors: anti-inflammatory, analgesic and anticancer activities.	Quinazolinones	30-44	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	120-125	
34338135-1	2021	Novel quinazolinones conjugated with indole acetamide (4a-c), ibuprofen (7a-e), or thioacetohydrazide (13a,b, and 14a-d) were designed to increase COX-2 selectivity.	Quinazolinones	6-20	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	147-152	
34071141-3	2021	Herein, we report the in vitro testing of some new quinoxalinone and quinazolinone Schiff"s bases as: antibacterial, COX-2 and LDHA inhibitors, and anticolorectal agents on HCT-116 and LoVo cells.	Quinazolinones	69-82	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	117-122