PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30257368-3	2018	METHODS AND MATERIALS: RCC cell lines ACHN and 786-O were treated with different concentrations (0-210 muM) of Scutellarin in vitro.	scutellarin	111-122	latexin	Homo sapiens	103-106	
30257368-10	2018	Treatment of RCC cells with Scutellarin (30, 60, and 90 muM) markedly induced apoptosis and cell cycle arrested at G0/G1 phase in a concentration-dependent characteristic.	scutellarin	28-39	latexin	Homo sapiens	56-59	
24802986-5	2014	Results demonstrated that scutellarin showed negligible inhibitory effects on the six major CYP isoenzymes in human/rat liver microsomes with almost all of the IC50 values exceeding 100 muM, whereas it showed values of 63.8 muM for CYP2C19 in human liver microsomes, and 63.1 and 85.6 muM for CYP2C7 and CYP2C79 in rat liver microsomes, respectively.	scutellarin	26-37	latexin	Homo sapiens	186-189	
24802986-5	2014	Results demonstrated that scutellarin showed negligible inhibitory effects on the six major CYP isoenzymes in human/rat liver microsomes with almost all of the IC50 values exceeding 100 muM, whereas it showed values of 63.8 muM for CYP2C19 in human liver microsomes, and 63.1 and 85.6 muM for CYP2C7 and CYP2C79 in rat liver microsomes, respectively.	scutellarin	26-37	latexin	Homo sapiens	224-227	
24802986-5	2014	Results demonstrated that scutellarin showed negligible inhibitory effects on the six major CYP isoenzymes in human/rat liver microsomes with almost all of the IC50 values exceeding 100 muM, whereas it showed values of 63.8 muM for CYP2C19 in human liver microsomes, and 63.1 and 85.6 muM for CYP2C7 and CYP2C79 in rat liver microsomes, respectively.	scutellarin	26-37	latexin	Homo sapiens	224-227	
22582896-5	2012	A mechanism study showed that scutellarin at doses of less than 10 muM induced cell cycle arrest at G0/G1 transition without the induction of cell apoptosis, which was accompanied by down-regulation of cyclin D1 and CDK4 expression.	scutellarin	30-41	latexin	Homo sapiens	67-70	
25858254-8	2016	RESULTS: Our results showed that mulberrin, scutellarin, quercetin, and glycyrrhetinic acid were strong inhibitors of OATP2B1-mediate E3S uptake with IC50 values being 1.8, 2.0, 7.5, and 13.0 muM, which were comparable with their plasma concentrations in clinical trials.	scutellarin	44-55	latexin	Homo sapiens	192-195	
22822035-7	2012	Among the major hepatic anion uptake transporters, organic anion-transporting polypeptide (OATP) 2B1 played a predominant role in the hepatic uptake of S-6-G and S-7-G and showed greater preference for S-7-G with higher affinity than S-6-G (K(m) values were 1.77 and 43.9 muM, respectively).	scutellarin	202-207	latexin	Homo sapiens	272-275